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A new adult dosing regimen of Amolin has been approved. Amolin is an antibiotic used to treat various respiratory-tract infections, including sinusitis, bronchitis, and pneumonia. In the new regimen, Amolin is administered twice a day (BID), every 12 hours, in contrast to three-times-a-day regimen used since Amolin was introduced in the United States. The BID regimen for more severe infections and infections of the respiratory tract consists of a new tablet containing 875 mg of amoxicillin and 125 mg of clavulanate potassium. In addition, the currently marketed tablet containing 500 mg of amoxicillin and 125 mg of clavulanate potassium can now be prescribed on a twice-a-day regimen for less severe infections that may be treated with a lower dose. Amolin should not be used in subjects with a history of allergic reactions to any penicillin or with a previous history of Amolin-associated cholestatic jaundice/hepatic dysfunction.

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