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Antioxidant defenses and its modulation by iron in carrageenan-induced inflammation in rats. No intraocular toxicity was found by the histopathology examination.

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Effects of acute systematic hypoxia on human urinary metabolites using LC-MS-based metabolomics. Imaging of reactive oxygen species and nitric oxide accumulation in vivo. Interestingly, genotypes with rapid growth on nitrate achieved similar growth with ammonium. Our study provides gene expression data that may be useful for future efforts to identify the putative CypA-dependent HIV-1 restriction factor and in studies of other cell-specific phenotypes.

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The functional properties of stromal cells from CYP-injected mice were tested with respect to stromal cell number and viability as reflected by the number of colony-forming unit fibroblasts, the ability of established stromal layers to secrete colony-stimulating factor and interleukin 6, as well as the capacity to support hemopoietic cells. Cardiac neuronal distribution and function can be imaged with standard gamma cameras and PET using radiolabeled analogs of norepinephrine. The Role of gsp Mutations on the Development of Adrenocortical Tumors and Adrenal Hyperplasia. The patient, a girl of 4 1/2 years, presented with the clinical signs of severe cerebral damage of acute onset and succumbed after an illness of 74 days.

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In children with pigmental nevus and melanoma, there was an impairment in the correlation of the parameters of tyrosine metabolism, the rate of free radical lipid peroxidation processes, and the status of the antioxidative system. Among these agents, intravenous pamidronate and zoledronic acid have demonstrated the greatest clinical benefit based on conservative endpoints.

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This observation was true for animals with either a slow or rapid recovery of body weight after the operation. Forty female relatives of these 23 DMD/BMD patients were diagnosed as carriers of the genes. Expression of members of Wnt and Frizzled gene families in the postnatal rat cochlea. Fathers then chose somewhat more altruistic, but mothers substantially less. Confocal laser microscanning analysis was used to observe insulin and glucagon expression.

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Protein synthesis can continue at the membrane, with the nascent peptide chain directly inserting into the ribosome-bound protein-conducting channel, the Sec61 complex. The study of the relationship between the epidural hematoma or subdural hematoma alcohol concentration (SDHAC) compared with femoral blood (BAC) and vitreous humor alcohol concentration (VHAC). Confocal Raman microscopy and fluorescent in situ hybridization - A complementary approach for biofilm analysis.

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The mechanism by which proteins fold from an initially random conformation into a functional, native structure remains a major unsolved question in molecular biology. Headache is an unusual symptom in patients with acute myocardial infraction. Relationship between ulcerative lesions of the duodenum and liver function Forty consecutive patients were enrolled and surgically treated with X Stop implantation.

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The results of this clinical study confirm and extend the observations originally made by Waxenberg and his colleagues in 1959, that testosterone deficiency in women produces a marked decrease in libido and sexual responsiveness. Western immunoblotting indicated that androgen receptor protein is significantly elevated in the levator ani relative to the extensor digitorum longus. Profound abnormalities in patterns of neuronal discharge were found as well as morphological and functional changes of glia in the epileptogenic scar. Erratum to: Criteria for ultrasound diagnosis of deep venous thrombosis of lower extremities. Morphologically, cells prefixed with glutaraldehyde were sperical at all lectin concentrations, with a continuous dense distribution of cell surface-bound con A, labelled directly with haemocyanin or indirectly using the peroxidase-diaminobenzidine reaction.

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Cardiovascular changes during laparoscopic cholecystectomy manifest by hypertension and tachicardia in the presence of increased central venous pressure and total peripheral vascular resistance, decreased stroke and cardiac indexes, decreased right-ventricular diastolic function, increased pressure in the pulmonary artery, and deceleration of venous bloodflow in the inferior and superior venae cavae. Expression of mutant Xdsh also inhibited elongation of neural tissues in vitro in Keller sandwich explants and in vivo in neural plate grafts. At the same time, the multi-faceted role of different T-cell subsets in IRI has gained interest, highlighting the dichotomous effects of differentiated T-cells and suggesting more selective therapeutic approaches. It is not always clear if specificity is determined by the genotypes of the interactors, or if phenotypic plasticity (sometimes called acclimation) plays a larger role. Prognostic factors for survival in lymphoma patients after autologous stem cell transplantation.

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The initial dosage of gemcitabine was 800 mg/m(2) weekly times three with 1 week off until progressive disease or adverse side effects prohibited further therapy. The use of portfolios can potentially provide flexibility in the summative assessment of doctors in practice. Initial management of patients with major burn injury requires airway support, fluid resuscitation for burn shock, treatment for associated trauma and preexisting medical conditions, management of adynamic ileus, and initial wound treatment. A Burkholderia pseudomallei outer membrane vesicle vaccine provides protection against lethal sepsis.

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In addition, hypoplastic thumbs were seen in two individuals in this family and should, therefore, be considered a true feature of TBS. After desferrioxamine infusion, both the ultrafiltrable and protein-bound aluminium increases significantly, probably due to mobilisation of aluminium from body tissues.

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Lithium dilution may be an acceptable substitute for the Fick principle as a means to measure CO in maximally exercising client-owned horses. Re-engineering hospital emergency rooms: an information system approach. Beyond crossing fibers: tractography exploiting sub-voxel fibre dispersion and neighbourhood structure.

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Where prenatal transfer occurs the fetal tissues across which the immunoglobulins pass are the yolk sac or the hemochorioplacenta. Many, if not most, homozygous males survive up to the third instar larval stage, but cannot pupate and die eventually as larvae. Protein structure and evolutionary history determine sequence space topology.

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However, VDAC-MMT-styrene and VDAC-MMT-toluene mixtures showed significant higher yield stresses than the other organoclay mixtures. MS analysis data are concerned especially with the base peak which is corresponding to C28H25N6O2S2 M ion. Transplantation of bone marrow mesenchymal stem cells on collagen scaffolds for the functional regeneration of injured rat uterus. Inward potassium rectifier current in type I vestibular hair cells isolated from guinea pig. Somatic mutations within the clonal sets enhanced binding to double-stranded DNA (dsDNA).

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The epidemiological significance of Pseudomonas aeruginosa in hospital sinks. The demonstration that basal enzyme activity and its responsiveness to the three agonists tested followed different evolution patterns during the cell cycle suggests that enzyme activity (or content) and activity (or number) of enzyme coupled receptors can be independently modulated. Genetic and epigenetic mechanisms contribute to motor neuron pathfinding. The independence of degradation from deadenylation is also found in vivo in transformed D. Piezoelectric Electromechanical Coupling in Nanomechanical Resonators with a Two-Dimensional Electron Gas.

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The aim of the study was intended to evaluate the association between certain rotational thromboelastometry (ROTEM) parameters with tissue plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1) levels and myeloma proteins in patients with MM and in controls. Five dimensions of wellness and predictors of cognitive health protection in community-dwelling older adults: a historical COLLAGE cohort study. While a host of management options have been considered to decrease this complication, neuromodulatory therapy has recently been advanced as an intervention that may be applied for this purpose.

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The future results of this research project will hopefully also contribute towards an increased focus on the growing number of individuals with visual impairment due to AMD among the Inuit. The purpose of this study was to determine whether stimulant users are at higher risk of a later cardiovascular event than are non-users, examining this association in both a national cohort and a population-based sample of children and adolescents diagnosed with attention-deficit/hyperactivity disorder (ADHD). Emphasis was given to Aspergillus and Penicillium species due to their relevance for mycotoxin production.

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Pharmacological interventions for clozapine-induced hypersalivation. subtilis led to decrease in resistance of isolated uropathogenic microflora to antibiotics. In this retrospective study of medical records spanning 1950 through 1995, the diagnoses of Crohn disease (CD), ulcerative colitis (UC), and MS were based on review of inpatient and outpatient records by a gastroenterologist and a neurologist. We present two patients with extreme reactive thrombocytosis (over 1,000 x 10(9)/l) due to intra-abdominal sepsis after liver transplantation. Magnetic resonance imaging in aortic valve, ascending aortic and isthmic aortic disease.

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Meanings of menopause: cultural influences on perception and management of menopause. We conclude that although cigarette smoke appears to induce changes in the vascular structure and to produce emphysematous lung destruction, the increased pulmonary arterial pressure in guinea pigs chronically exposed to smoke is not directly related to either of these findings. The essential oil mixture did not provide a better skin protectant effect than standard care.

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A universal strategy to prepare functional porous graphene hybrid architectures. When the homeostasis model assessment (HOMA) index exceeded 2.0, the subject was considered to have IR. A significant change in force balance was found between the right and left sides over time and the difference between the two sides decreased with the time post-injection, reaching a minimum at 12 weeks. Increasing risk factors are making leishmaniasis a growing public health concern for many countries around the world.

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Treatment of cultured Molt-4 human leukemia cells with enediyne resulted in a time-dependent depletion of glutathione (GSH) whereas the exposure of the cells to the GSH precursor N-acetylcysteine (NAC) resulted in a substantial suppression of this effect. Reclaiming futures: communities helping teens overcome drugs, alcohol and crime--a new practice framework for juvenile justice.

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Molecular biological targeting refers to selective expression of the therapeutic gene by the target cell through the use of selective promoters. The outcomes were follow-up models and grade 3, 4, and 5 adverse reactions. We report a case of severe hyponatraemia and hypoglycaemia in a patient with complicated falciparum malaria. Fluorescence microscopic imaging technology was used to observe the changes of the endogenous fluorescence signals of NADH and FAD in the energy metabolism pathways.

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Field evaluation of energy expenditure in women using Tritrac accelerometers. Sucrose synthase (SuS) expression was studied in the filamentous, nitrogen-fixing cyanobacterium Anabaena sp. In patients who experienced grade 4 hematological toxicity during the prior chemotherapy, the doses of cisplatin and irinotecan were reduced to 15 and 50 mg/m(2), respectively. In addition, the angle of inclination decreases at the low range of the viscosity ratio of internal to external fluids and increases at the high range.

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Annotation of sequences that share little similarity to sequences of known function remains a major obstacle in genome annotation. Meanwhile, HDL-C decreased with the two anthropometric measurements.

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For many of these patients, the length of the stricture is too long to perform the tension-free anastomosis technique. Many real networks present a bounded scale-free behavior with a connectivity cutoff due to physical constraints or a finite network size. Dopamine as a Novel Electrolyte Additive for High-Voltage Lithium-Ion Batteries. Increased adrenergic drive causes vasoconstriction and vessel resistance maintaining MAP, while increasing peripheral vascular resistance and conduit vessel stiffness. The chemistry of such systems is not well known and ESMS is a powerful technique for studying the reactions of clusters in solution.

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This treatment did not increase cytochrome P-450 cytochrome c reductase or microsomal protein nor does it appear to affect the binding of aniline to cytochrome P-450. Transurethral biopsy sampling is unreliable for detecting prostate cancer in men with clinically significant BPH. Further, their potential for gene delivery to the mouse lungs in vivo was examined. We utilized these gene sets, hierarchical clustering (HC), and Kaplan-Meier analysis, to examine 309 STS, using Affymetrix chip expression profiling. ESR correlated most closely, followed by the IgM concentration of circulating immune complexes, hemoglobin, C3A, and fibrinogen.

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The results revealed that BMCs accumulated more in the damaged liver than in the intact liver. RA promotes proximalization of limb cells and endogenous RA signaling is required to maintain the proximal Meis domain in the limb.

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Locating community food and water supplies near shelters, providing transportation to medical care, and public-health visits to shelter locations helped prevent the development of long-term park encampments. To evaluate the clinical efficacy and safety of tissue-selecting therapy (TST) in treatment of mixed hemorrhoids.

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To present a dramatic case of simultaneous bilateral central retinal vein occlusion associated with leukemia and anticardiolipin autoantibodies. Pneumocystis carinii pneumonia in patients with ulcerative colitis treated with corticosteroids. To optimize the ocular drug delivery, high molecular weight cellulosis and PVA polymeric films were prepared.

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This review is a summary of the clinical syndromes caused by Leishmania and treatment regimens currently used for various forms of leishmaniasis. Sudden Cardiac Death After Non-ST-Segment Elevation Acute Coronary Syndrome. Human otolith-ocular reflexes during off-vertical axis rotation: effect of frequency on tilt-translation ambiguity and motion sickness.

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Future trials in similar settings should consider offering more support in centers with high turnover of staff and offering alternative methods of payment when families experience financial difficulties in purchasing the subsidized restraints. Laparoscopic calicovesicostomy in the horseshoe kidney with ureteropelvic junction obstruction associated with ipsilateral ureteral duplication and a large-capacity bladder is described. The results show significantly higher number of live births per 1000 and birth-rate in studied women as compared to the total population of a district. Recently, laparoscopy has become popular in the management of impalpable testes. Histological studies showed characteristic structures of heart tissue, including elongated cardiomyocytes, well-differentiated sarcomeres, and gap junctions within the grafts.

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Requirement of arteriovenular pairing for increased capillary filtration during acute inflammation. Many of these genes are regulated by a transcriptional cascade involving two transcription factors: the forkhead protein Sep1p which activates the zinc finger protein Ace2p. The influence of inorganic ions (HCO(3), PO(4)/HPO(4)/H(2)PO(4), Cl, SO(4), Ca, Na and Mg) on the advanced chemical oxidation process of organic compounds dissolved in water is reported here. This, to the best of our knowledge, is the longest follow-up report of an acute exogenous LP patient and the only case that demonstrates non-resolving abnormalities in a pediatric patient after a single acute episode of mineral oil aspiration. Oncocytic metaplasia of the pharynx has been infrequently described, with only two previous cases in the literature.

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Chronic mercury exposure impairs the sympathovagal control of the rat heart. Our experience strongly recommended the first-line use of SRAE for severe renal hemorrhage. Three parapatric taxa were proposed for the area: Callicebus caligatus, Callicebus stephennashi, and Callicebus dubius, but the latter has recently been considered a synonym of C. Nanomechanical probing of the septum and surrounding substances on Streptococcus mutans cells and biofilms. An exome sequencing strategy to diagnose lethal autosomal recessive disorders.

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Difficulties in microsurgical treatment of aneurysms after coiling Long-term follow-up is required from other randomised trials to establish the effects of lower or less frequent doses of aspirin. Genome-wide association studies (GWAS) have identified more than 8900 genetic variants, mainly single-nucleotide polymorphisms (SNPs), associated with hundreds of human traits and diseases, which define risk-associated loci. Problems and achievements in anesthesiology and intensive care in contemporary oncological surgery

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During administration of crystalline amino acids without dextrose, nitrogen balance improved substantially from control values obtained during dextrose infusion, while the level of serum-free fatty acids and ketone bodies rose and that of serum immunoreactive insulin fell. Cancer detection rate was calculated according to symptoms described by patients, IPSS and age groups. Stroke is the most frequent neurological disorder, and the most common cause of severe disability compared to other diseases. Metals in tissues of migrant semipalmated sandpipers (Calidris pusilla) from Delaware Bay, New Jersey.