A new adult dosing regimen of Claneksi has been approved. Claneksi is an antibiotic used to treat various respiratory-tract infections, including sinusitis, bronchitis, and pneumonia. In the new regimen, Claneksi is administered twice a day (BID), every 12 hours, in contrast to three-times-a-day regimen used since Claneksi was introduced in the United States. The BID regimen for more severe infections and infections of the respiratory tract consists of a new tablet containing 875 mg of amoxicillin and 125 mg of clavulanate potassium. In addition, the currently marketed tablet containing 500 mg of amoxicillin and 125 mg of clavulanate potassium can now be prescribed on a twice-a-day regimen for less severe infections that may be treated with a lower dose. Claneksi should not be used in subjects with a history of allergic reactions to any penicillin or with a previous history of Claneksi-associated cholestatic jaundice/hepatic dysfunction.
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