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Dutagen (Dutasteride)
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Dutasteride

Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal mediator that plays a role in the development and enlargement of the prostate gland. Dutagen was approved by the FDA in 2001 for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist tamsulosin to enhance the therapeutic response. Its clinical efficacy against benign prostate hyperplasia in male patients is comparable to that of finasteride, a specific type II 5α-reductase inhibitor. However, unlike finasteride, Dutagen is not yet indicated for the treatment of androgenic alopecia although it was demonstrated to be effective in several randomized, double-blind, placebo-controlled trials in androgenetic alopecia.

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Dutasteride, Deetor, Duodart, Duprost, Dutagen, Dutas, Dutasterida, Dute, Veltride,

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We have found early and aggressive work-up, as outlined herein, to be helpful in the successful treatment of occult cardiac injuries. Measurement of the 3D Born-Oppenheimer potential of a proton in a hydrogen-bonded system via Deep Inelastic Neutron Scattering: the superprotonic conductor Rb(3)H(SO(4))(2). Administration of aldrin (2 or 5 mg/kg/day, p.o.) enhanced LA of rats and reached a maxima after 12 consecutive days of treatment following which aldrin-induced LA was gradually reduced and restored to control value after 20 consecutive days of aldrin treatment.

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Many biological networks, including transcriptional regulation, metabolism, and the absorbance spectra of metabolite mixtures, can be represented in a bipartite fashion. The incidence and severity of heterotopic ossification after sixty-five consecutive primary uncemented total hip replacements were compared with those after seventy consecutive primary hybrid total hip replacements (consisting of an uncemented acetabular component and a cemented femoral component).

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Age- and sex-specific incidence rates were calculated, using census data. The primary outcomes were shoulder function or disability, pain and treatment failure (defined as the number of participants who had been given a non-routine secondary surgical intervention (excluding hardware removal) for symptomatic non-union, malunion or other complications).

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Mesomucinase (hyaluronidase) and experimental tetanus intoxication Here we describe a bizarre fly larva (Diptera), Qiyia jurassica gen. Neurological examination revealed rigidity in the neck and limbs, with motion and speech being generally slow. Following Day 3 embryo biopsy and genetic analysis, embryos were transported back to the Center for Assisted Reproduction for Day 5 embryo transfer.

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The in vitro inhalation study was performed using the cascade impacted method. Huntingtin-interacting protein 1 (HIP1) and HIP12 are orthologues of Sla2p, a yeast protein with essential functions in endocytosis and regulation of the actin cytoskeleton. An efficient Hydrofluoric acid (HF) based technique was used for rapid and specific binding of L.

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Colorimetric estimation of p-acetamidobenzaldehyde thiosemicarbazone in blood. Developmental correlates of different types of motor imitation in young children with autism spectrum disorders.

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The impact of funding deadlines on personal workloads, stress and family relationships: a qualitative study of Australian researchers. Postnatal ultrasonography is a reliable measure of gross renal parenchyma, and in the presence of vesicoureteral reflux correlates with renal scintilligraphy.

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Serum insulin-like growth factor-I (IGF-I) increased twofold during the growing phase, then remained at that level. Recent advances in the fabrication of AIEgens-functionalized inorganic-organic hybrid materials and their applications in biomedicine, chemical sensing, and solid-state light emitting are presented. Myosin adenosine triphosphatase staining was employed to investigate whether muscle lesions in the elongated soft palate (ESP) of dogs with BAOS reflect the presence of denervation. A detailed characterization of a conventional low-flow electrospray ionization (ESI) source for mass spectrometry (MS) using solution compositions typical of reversed-phase liquid chromatography is reported. Comparison of Single-Incision and Conventional Multi-Port Laparoscopic Distal Gastrectomy with D2 Lymph Node Dissection for Gastric Cancer: A Propensity Score-Matched Analysis.

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It is recommended that intravenous immunoglobulin be infused at a rate of not less than 8 hours per day and that factors predisposing to thromboembolism such as dehydration, immobilisation and low blood pressure be avoided for the duration of at least two half-lives of immunoglobulin (6 weeks). The results of this study provide helpful 3-dimensional volumetric information to the limited existing data on margin requirements for whole stomach radiation therapy. Board of Directors instructs MSMS to support arbitration as means of setting liability disputes.

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The aqueous extract of young leaves of Holarrhena africana, a plant used in the Nigerian traditional medicine, exhibited good activity against Trypanosoma brucei spp. Thus, during invasion of the foregut by vagal-derived neural crest cells, expression of Gdnf was restricted to the mesenchyme of the stomach, ahead of the invading NC cells.

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Therefore, the conclusions gained are to be interpreted to the effect that they are statistically vertifiable for a selected patient group with a therapy period of 4 months or longer. One of the reasons for patient nonresponse to cardiac resynchronization therapy is a suboptimal left ventricular (LV) pacing site. The aim of this paper is to review the modification performed in GIC-based materials to improve their physicochemical properties. Genomic estimated breeding values for milk yield were estimated using 2 prediction methods, GBLUP and BayesC, and accuracies were calculated as the correlation between yield deviations and genomic breeding values included in the estimation process, mimicking the situation for young bulls. The expression patterns of pair-rule gene orthologs in representatives of other arthropod groups imply that these genes were segmentation genes in the last common ancestor of the various arthropod groups, but almost nothing is known about the underlying mechanism in noninsect arthropods.

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Conservative management of dermal sinuses is not justified, and these lesions should be electively resected at the time of diagnosis. Here, we report the fine characterization of two different deletions in the USP9Y gene (one of the two candidate genes in the AZFa region), which have been transmitted through natural conception in two unrelated families.

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Specifically, retardation of expiratory airflow is effected by the major adductors of the larynx, the thyroarytenoid (TA) muscles. Shaken infant syndrome: developmental neuropathology, progressive cortical dysplasia, and epilepsy. Cardiac rupture after acute myocardial infarction (AMI) in patients with aortic valve stenosis (AS) is uncommon and only 2 survival cases after surgery have been reported to date. Recent advances in intravenous delivery to the brain have exploited receptor-mediated transcytosis and BBB disruption, as well as control of carrier properties.

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Cluster randomized trial of a multilevel evidence-based quality improvement approach to tailoring VA Patient Aligned Care Teams to the needs of women Veterans. Hemicentral retinal vein occlusion associated with ocular hypertension and clotting abnormality. This article tests the hypothesis that extensive kinship systems best characterize hunter-gatherer societies, whereas more intensive forms of subsistence, like horticultural, agricultural, and pastoral economies, are more likely to have intensive kinship systems. Henry Fogg (1707-1750) and his patients: the practice of an eighteenth-century Staffordshire apothecary. The clinical diagnostic value of dexamethasone suppression test in depressive illness.

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Transient transfection experiments demonstrated that ERalpha and ERbeta induced the highest levels of transcription with the A2 ERE, intermediate levels of transcription with the OT ERE, and low levels of transcription with the pS2 and B1 EREs. Severity of sports-related concussion and neuropsychological test performance. It was also found in some two-rowed landraces originating from Spain and Morocco. The importance of optimizing the vessel length and securing reliable vascular control are critical for procedures like laparoscopic donor nephrectomy.

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In a new experimental approach cells were cultivated in the presence of N-propanoyl- D-mannosamine. Multiple octamer-binding proteins are targets for the cell cycle-regulated nuclear inhibitor I-92. Tea, its health effects and other benefits have been described in detail with an introduction about the origin of tea.

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For once-suggested items, the warning had the unintended effect of improving old/new recognition of the suggested information at retest, an effect that offset the improvements in source discrimination accuracy conferred by the warning. The role of the sodium, potassium, magnesium and calcium ions in the transfer of energy at the level of the ATP molecule. Hemicellulose polysaccharides represent a large group of natural renewable polymers, however, their application potency is still low.

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The impact of population structure on association studies undertaken to identify genetic variants underlying common human diseases is an issue of growing interest. The additional, small pool of this glycoprotein is known to exist in the alpha granules of bone marrow megakaryocytes and blood platelets. Plain radiographs of the shoulder, humerus, elbow, forearm and wrist demonstrated no fractures. The same metabolite was detected in bile from rat liver perfused with retrorsine, which is a diester alkaloid similar to monocrotaline, whereas it was not formed from heliotrine, an alkaloid lacking the 7-ester function. Clinical diminution of intoxication should not be more rapid for children and adolescents than it is for adults.

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Driver genes and its clinical significance in non-small cell lung cancer It was found that the number of PC molecules in the multilayer increased with increasing initial lipid concentration in the dialysis mixture. A non-invasive estimation of cerebral perfusion pressure (CPP) using transcranial Doppler sonography was assessed in brain-injured patients by comparing conventional measurements of CPP (difference between mean arterial pressure and intracranial pressure) (CPPm) with the difference between AP(mean) and the critical closing pressure of the cerebral circulation (CPPe).

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Cor triatriatum of the left atrium thought to be an anomaly of the embryonic pulmonary venous connection to the left atrium. Catching errors with patient-specific pretreatment machine log file analysis.

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Thymidylate synthase (TS) and thymidine phosphorylase (TP) are important enzymes involved in the de novo DNA synthesis and the salvage pathways for pyrimidine, respectively. Direct effects of incubation temperature on morphology, thermoregulatory behaviour and locomotor performance in jacky dragons (Amphibolurus muricatus).

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Since these products have been optimized for adhesive purposes, the aim of this study was to develop optimized resins for the infiltration of enamel lesions and to measure their physical properties. We measured the thickness of abdominal muscles of eight patients preoperatively, and postoperatively after 1 year, using magnetic resonance imaging (MRI). This study presents for the first time data on glutamine intake in preterm and term neonates fed human milk. Chronic cough: from a complex dysfunction of the neurological circuit to the production of persistent cough.

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To investigate the involvement of dietitians in research and audit and to assess their understanding of and attitudes towards these activities. When selecting genes with controlling the same FDR level, our methods have on average a significantly lower false discovery rate in exchange for a minor reduction in the power. In the present study, a seven-year data set on the autumnal moth, Epirrita autumnata (Borkhausen) (Lepidoptera: Geometridae), was used to analyze whether the body weight-fecundity relationship in this capital breeding, cyclic forest defoliating lepidopteran is constant across years. Moreover, the discrepancy between the results of corneoscleral rim cultures and subsequent endophthalmitis renders them invalid as a quality assurance procedure. A vegetarian diet, preceded by a period of fasting, can be a useful supplement to conventional treatment of rheumatoid arthritis, a medical team from Oslo has claimed.

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Mechanism of competitive action of isonicotinic acid hydrazide and vitamin B6. Here we identify an alternative mechanism by which NKT cells influence the strength of T cell responses: through modulation of peripheral dendritic cell (DC) trafficking. We sought to determine whether an imbalance between angiogenic and antiangiogenic factors exists in asthmatic airways. The parallel development of adjuvants along with better HIV-1 immunogens will be needed for a successful AIDS vaccine. Thus, we have developed a rapid and inexpensive vertebrate model that can enhance diabetes drug discovery by preselecting hits from chemical library screens, before testing in relatively expensive rodent assays.

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Such analyses have applications in the study of microbial communities. The presence, according to GC - MS analysis, of natural inhibitors of transamidinase (compounds of thiourea and its metabolites, the group of mercaptopurines and mercapto-derivates of imidazole) in peripheral blood at the maximum level--0.71 to 0.78 mmol/l on days 7 to 10 upon the onset of the disease--is a prognostically favorable criterion.

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The structure of the O-polysaccharide from Pseudomonas stutzeri OX1 containing two different 4-acylamido-4,6-dideoxy-residues, tomosamine and perosamine. Changes in physiologically active BT concentration may be a vulnerability factor for depressive symptoms in middle-aged depressed men.

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Human cytomegalovirus (HCMV) glycoprotein gB promotes virus entry in trans acting as the viral fusion protein rather than as a receptor-binding protein. Hypoxia-responsive element-mediated soluble Tie2 vector exhibits an anti-angiogenic activity in vitro under hypoxic condition. The composition of the FoxO-Smad synexpression group suggests that stress reactions and adaptive functions accompany the cytostatic response of keratinocytes to TGF-beta.

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Techniques for application of tissue adhesive for corneal perforations. Structural evaluation of a mimicry-recognizing paratope: plasticity in antigen-antibody interactions manifests in molecular mimicry. Propafenone in a usual dose produces severe side-effects: the impact of genetically determined metabolic status on drug therapy.

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A 21-year-old Malay man with no previous known medical illnesses presented with a sudden onset of peripheral corneal perforation. Electron arc therapy of the chest wall for breast cancer: rationale, dosimetry, and clinical aspects. Pervasive isoform-specific translational regulation via alternative transcription start sites in mammals.

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Satisfaction of search (SOS) occurs when an abnormality is missed because another abnormality has been detected. Moreover, PARPis exhibit very little effect on cancers that are proficient for DNA repair and clinical efficacy for PARPis as single-agent therapies has yet to be illustrated. F-like proteins, present only in group I nucleopolyhedroviruses (NPVs), are remnant, nonfunctional F proteins. The multifunctional catheter enabled simultaneous measurement of the intravascular pressure and liner flow rate in large vessels (both arteries and veins).

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New strategies in myelofibrosis: the evolving paradigm of disease pathogenesis, prognostication and treatment. In elephant Mb, new interactions resulting from the conformational change accompanying ligand binding may be responsible for the increased CO binding.

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Here we present a link between the B cell signaling and internalization machinery and show that Src-family kinase activity is required for inducible clathrin heavy chain phosphorylation, BCR colocalization with clathrin, and regulated internalization. Continuous subcutaneous infusion of glucagon by portable pump in non beta cell tumor hypoglycemia. The best views for each of the individual ligaments were determined. The high-volume CVVH is distinctly superior in preventing sepsis-related hemodynamic impairment.

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Our findings allow us to confirm that salinity is the main factor acting on dissolved Cd bioaccumulation processes. Entrainment could occur from different stimulation sites with the stimulated impulses from each site activating the circuit with a different pattern. This clinical observation is the occasion to review the pathophysiology of this lesion and the last developments in the surgical treatment.

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Effects of retroviral infections on immune function in African-American intravenous drug users. Molecular basis of adaptive convergence in experimental populations of RNA viruses. Twenty of them had OSD (study group) and the remaining 15 adolescents constituted the control group. Nitric oxide (NO) participates in the regulation of many cell functions in the CNS, including modulation of ion channel function by direct changes in the channel protein structure, modulating permeability or gating kinetics. Practical ways of caring for these high-risk pregnancies are outlined, emphasising the continuous search for entanglement of umbilical cord by ultrasound and cardiotocography.

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Cold-stress tests are used for evaluating vascular disorders in the hand-arm vibration syndrome, and the value of such tests based on finger skin temperature measurement has been investigated. There may be a few cases where it is morally better to use a never sentient human than a sentient animal, but these cases are few and would not fulfill the current need for research subjects. Only a few nonnuclear weapons states with uranium-fueled power plants have kept the weapons option open, and none has evidenced activities intended for diverting fissionable material from its civilian system. The next 5 years of global HIV/AIDS policy: critical inosine 500 mg tabletki dawkowanie augmentin gaps and strategies for effective responses.

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