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Endoxana (Cyclophosphamide)

Endoxana is used in the treatment of chronic lymphocytic leukaemia, lymphomas, soft tissue and osteogenic sarcoma, and solid tumours. It is given orally or intravenously. Endoxana is inactive until metabolized by the liver. Before you begin treatment with Endoxana, you and your doctor should talk about the benefits of this medicine as well as the risks of using it. This medicine is available only with your doctor's prescription.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Zolacos, Danoxilin, Prazolan, Rosasol, Spektramox, Tacrolimus, Taclar, Gastracid, Clopivas, Trexen, Clopidogrel, Metazol, Cravit, Ciclofosfamida, Stemzine, Aclam, Hepcinat, Simox, Clabel, Ovelquin, Citox, Drylin, Allerfex, Prochlor, Aknet,

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The relative resistances (IC50 values of transfectants/those of NIH3T3 cells) to cisplatin, adriamycin, 4-hydroperoxycyclophosphamide, melphalan, and CPT-11 were 2.1, 1.6, 4.7, 4.9, 1.6, respectively for nm-1 and 1.6, 2.2, 3.3, 9.1 and 2.2, respectively for nm-2. Newer surgical strategies for repair of the heart defect may delay or prevent the development of arrhythmias and are being actively pursued. Histological assessment for mucosal atrophy and inflammation was performed in gastric biopsy specimens taken from 24 Japanese patients with PA and from 24 age- and sex-matched controls.

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Practical Os/Cu-cocatalyzed air oxidation of allyl and benzyl alcohols at room temperature and atmospheric pressure. The purpose of this work is to present, for the first time, a new type of temporary extraluminal shunt, connecting the femoral to the internal carotid artery with the interposition of a roller pump to regulate the blood flow. Sm14 is a 14-kDa vaccine candidate antigen from Schistosoma mansoni that seems to be involved in cytoplasmic trafficking of fatty acids. The mouse cerebellar cortex in organotypic slice cultures: an in vitro model to analyze the consequences of mutations and pathologies on neuronal survival, development, and function. Previously described metrics for surgically treated oral cavity cancer are not prognostic for surgically treated laryngeal SCC.

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A thorough search of the pertinent health science databases was conducted, including the Education Resource Information Center (ERIC), MEDLINE, and EMBASE, and faculty development books and relevant information found were reviewed in order to provide recommendations for best practices. selective carbon-carbon bond formation for the functionalization of heterocycles. Palsy of the hypoglossal nerve is frequently associated with other cranial nerve palsies and can be related to vascular, neoplastic, infectious or traumatic conditions. A clinical classification of vestibular disorders, with differentiation of three syndromes and discussion of a common form of vertigo induced by sudden movement of the head. Influence of lysine acetyl-salicylate on glucose and arginine stimulated insulin release in man.

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Stem Cell Leukemia: how a TALented actor can go awry on the hematopoietic stage. Evaluation of a noninvasive system for determining left ventricular filling pressure.

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Herein we report on a case of adenomatoid tumor apparently originating from the ejaculatory duct which to our knowledge has not been reported previously. Additional references were identified with related article searches. Focal necrotic lesions of the epithelial layer were present containing HSV-specific antigens. Technetium-99m-labelled hexakis-methoxy-isobutyl isonitrile (Tc-99m-MIBI) is a substrate for P-glycoprotein (P-gp), an ATP-binding cassette (ABC) transporter protein, and can be used to image P-gp expression. MR monitoring is a highly sensitive technique that is applicable to muscle stem cell transplantation.

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NTBI may play a catalytic role in free radical reactions in the presence of cellular reductants such as NADPH. LIM and SH3 domain protein 1 (LASP-1) overexpression was associated with aggressive phenotype and poor prognosis in clear cell renal cell cancer. Three-dimensional thermoluminescence (TL) spectra based on temperature, wavelength and intensity for newly developed LiF:Mg,Cu,Na,Si TL material at the Korea Atomic Energy Research Institute (KAERI) were measured and analysed.

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Thoracic sympathectomy is recognized as an effective treatment for patients with severe hyperhidrosis. Among genes preferentially expressed in the zebrafish pineal gland, we identified a tissue-specific form of the unc119 gene family, unc119c, which is highly preferentially expressed in the pineal gland during day and night at all stages examined from embryo to adult.

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Determination of sensitivity versus frequency characteristics of miniature ultrasonic hydrophones below 1 MHz using planar scanning technique. Our results confirm that murine DGAT2 has only two transmembrane domains but also can interact with membranes via a previously unidentified helical domain containing its active site. More frequent side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions.

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Such disorders may be more easily identified as being caused by the work rather than by exposure to hand-transmitted vibration per se. In contrast, the neighboring granulosa cells were not reactive to any of the three antibodies used.

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Clinical application of image-guided radiotherapy, IGRT (on the Varian OBI platform). To evaluate whether lymphvascular space involvement (LVSI) is a risk factor for relapse of disease and lymph node metastasis in endometrial cancer. The follow-up results from the initial 21 RALP M-R participants are presented. ERP results showed that affective states with high motivational intensity induced smaller N2 and greater late positive potential (LPP) amplitudes than low motivational intensity and neutral affective states.

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These concentrations are in the same range as those expected to be present in vivo during the wound healing process. We studied the status of IFN-gamma-induced CIITA messenger RNA (mRNA) accumulation and CIITA-driven transactivation in IFN-beta-treated cells and used cell lines that had defined defects in the type I IFN response pathway to address the roles of IFN signaling components in the inhibition of MHC class II induction. The bactericidal effect of surface-active agents on tubercle bacilli.

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New surgical approach to device closure of multiple apical ventricular septal defects Thus, the quality of life became a critical variable in determining the effectiveness of mental health treatment. A new technique for continuous recording of penile rigidity and tumescence has been developed.

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Together, our results support the notion that Gal-3 and sFbg are two physiological mediators present at inflammatory sites that activate different components of the MAPK pathway and could be acting in concert to modulate the functionality and life span of neutrophils. Therefore, there is an urgent need to evaluate the recharging performance through long-term observations. Obesity in children: recent advances and recommendations for treatment

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LBW and SGA Impact Longitudinal Growth and Nutritional Status of Filipino Infants. In single-fiber recordings, cowhage, histamine and/or capsaicin were applied to the cutaneous receptive field of 43 mechano-heat-sensitive C-fiber (CMH) nociceptors. This finding indicates a peripheral suppression of AVP levels that is most likely due to a regulatory set-point shift toward hypotonic hyperhydration, rather than to a reduced central capacity of AVP secretion. In this study the investigators compared the commonly used Fisher scale with 2 newer radiographic scales for the prediction of vasospasm, delayed infarction, and poor outcome.

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A new electrically heated carbon paste electrode has been developed for performing adsorptive stripping measurements of trace nucleic acids. Possible role of high-dose busulfan in second reciprocal transplant between brother and sister for resistant acute leukemia. The all-in-one adhesive showed different behavior depending on whether the enamel surface was dry or wet. Parathyroid tumors in atomic bomb survivors in Hiroshima: epidemiological study from registered cases at Hiroshima Prefecture Tumor Tissue Registry, 1974-1987. Their methodology, planning, and targeting for their firesetting behavior, as well as reported motivations for engaging in arson, are also considered.

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In these difficult cases, intracorporeal electrohydraulic lithotripsy (EHL) is a method that allows large stones to be fragmented and removed percutaneously or endoscopically. It is postulated that alpha-adrenergic mechanisms are involved in these interactions.

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Association with EBV may also be observed in sporadic cases, and detection of EBV gene products may aid their diagnosis. Feeling pain is in the same time a sensory and an affective experience.

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Allograft safety: viral inactivation with bone demineralization. We could not observe any gross alteration in circadian rhythmicity nor any enhanced sensitivity towards ethanol in the mutant mice. At the same time, both the deviation S and difference (Tcal -Tm ) enlarge with the temperature melting range of the helix-coil transition.

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In a study of 112 cases of invasive breast cancer, the prognostic value of the gradient of nuclear volume (NV) changes was examined. Prevention, diagnosis, and treatment of viral infections in patients with hematologic diseases

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A 31-year-old, white woman, gravida 4, para 2012, at term underwent an uncomplicated spontaneous vaginal delivery. This has emphasized the need for a multifaceted approach, initially directed against the stress of bypass and secondly against the reperfusion phenomenon. Sheep have been used successfully in previous studies to examine the interaction of bone turnover and ovariectomy.

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These findings indicate that infections may have a relevant role in the pathophysiological mechanisms of suicidal behavior. Actin-destabilizing factors disrupt filaments by means of a time reversal of polymerization. Paired psychological contract reports were obtained from 80 employee-employer dyads in 16 university-based research centers. A glycerol-requiring mutant of Bacillus subtilis formed irregular spheres and showed disturbed septum formation, when subjected to growth limitation by the supply of glycerol.

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To determine whether rates of adherence to risk reducing behaviors were affected by depressive status during hospitalization and 3 months later. Fourteen pesticide residues from current agricultural practice were detected in CGT. Age-related changes in prefrontal activity during walking in dual-task situations: a fNIRS study.

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Immunologic studies have confirmed the benign nature and specificity of reactions to injectable collagen. Of relevance to industry is whether any changes in expression levels might occur as a consequence of storage of the modified strains. The rarity of prion diseases in this country makes it difficult to remember and put into practice specific preventive measures in suspected and diagnosed cases. The Effect of Human Genome Annotation Complexity on RNA-Seq Gene Expression Quantification. These observations suggest that oscillatory contractile activity in tail arteries from SHRSP is caused by an abnormal variation in potassium efflux during stimulation with norepinephrine.

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This study found intranasal administration of hydromorphone in patients experiencing vasomotor rhinitis had acceptable bioavailability and a pharmacokinetic profile comparable to previous studies. Isolation and characterization of clones encoding cockroach allergens. Prevalence of multiple antibiotic resistance in Neisseria gonorrhoeae.

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We aimed to determine the predictive factors for excellent or extremely poor functional outcome in patients with first-ever atrial fibrillation (AF)-related cardioembolic stroke. Sensor and arterial blood gas measurements were monitored up to 68 hrs.

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Substances toxic for biosynthesis of penicillin accumulated in the medium at the end of the process during penicillin fermentation. Fabrication of integrated porous glass for microfluidic applications. Submicroscopic structure of the membrane apparatus of methanotrophic bakteria Adhesions, maxillary sinus mucosal swelling, secretions, and ostium obstruction were also endoscopically evaluated. Origin efficiency may result from Mcm5 protein assuming an altered conformation, as predicted from the atomic structure of an archaeal MCM (for minichromosome maintenance) homologue.

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Here we present the first detailed study of PCR amplification of random DNA libraries used in aptamer selection. To evaluate whether 1018 ISS has activity in subjects with allergic asthma. The effects of temperature shifts on trehalose levels are opposite the effects on polyols and more dramatic. To investigate whether borneol could open the BTB by affecting TJ-associated proteins ZO-1, occludin, claudin-5 and F-actin in the rat model of C6 glioma.

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A considerable benefit was noted from the additional acoustic information in conditions of reverberation and reverberation plus noise. During the post-dosing period Se concentrations and GSHPx activities fell to levels which were in most cases somewhat higher than baseline values. Functions for cost and benefit of altruism are derived from the fitness functions. Since the intrahepatic ducts are never seen at surgery, the authors stress the importance of preoperative and operative cholangiography in locating such anomalies.

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Integrated risk reduction framework to improve railway hazardous materials transportation safety. Further studies are needed to unravel the genetics of diabetes in South Asians .

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For this reason, the algorithm includes a second stage that pulls the interatomic distances towards more fully representative values. The mechanism of cytoprotection is unrelated to alterations in the coagulation cascade and may involve inhibition of complement activation in response to tissue injury.

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There is therefore a strong rationale for developing new antidiabetic agents aimed at restoring or replacing early prandial insulin secretion and thereby curbing mealtime glucose excursions in patients with type 2 diabetes. We demonstrate that saccade-dependent spatial and temporal mislocalisation are absent in subject A.I.

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The system must be able to capture accurate encounter data for outcomes analyses and capable of use by multiple health plans for their unique policies or programs such as disease management. Additional study is needed to determine whether changes in ECM remodeling and neovascularization of the mammary gland result in increased milk yield during increased milking frequency, or occur in response to an increased demand for milk production. This study examined the effects of ADPRT Val762Ala and XRCC1 Arg399Gln polymorphisms on ADPRT-XRCC1 interaction in vitro in cells and their contributions to gastric cardia adenocarcinoma (GCA) risk. With chondroitin-4SO(4) as the substrate, the recombinantly expressed chondroitinase AC has a K(m) of 0.8 microM and a k(cat) of 234 s(-1). Stroke or systemic embolism (primary outcome), major bleeding (safety outcome), and mortality were examined in relation to renal function over time estimated with both the Cockcroft-Gault and Chronic Kidney Disease Epidemiology Collaboration equations.

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They include DNA repair, cell cycle checkpoints and apoptosis, and are probably key to the relative selectivity of camptothecins toward cancer cells and to clinical resistance. A 13-year retrospective study was undertaken to determine the incidence of posttonsillectomy trifamox 500 mg para que sirve hemorrhage, to evaluate potential risk factors, and to assess the efficacy and safety of ambulatory tonsillectomy. The test hypotheses were examined using separate Poisson regression models, which adjusted for spatial autocorrelation.

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He was diagnosed in D phase, silenor dosage forms of cephalexin with decompensated heart failure, which was refractory to treatment, and after several incidents of malignant arrhythmias, the patient died. Degenerative alterations of the autonomic nervous system are evident in all three groups with most pronounced changes in the pale granular type of sialadenosis.

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This meta-analysis showed that RANTES -403 G/A polymorphism was a risk factor for asthma, while -28C/G polymorphism were not associated with asthma. In most cases, chemical clopidogrel mode of action pptx treatment therefore has been considered to give lower investment and operating costs than biological treatment. Injury and game attendance data were collected using monthly telephone interviews throughout the season. In total, eight articles met the eligibility criteria, among which, two studies about NAFLD, four studies about NASH, and three studies about CHC, were identified and included in the meta-analysis.

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Electrolyte problems in the surgical patient, with particular reference to serum calcium, magnesium and potassium levels. Mycobacteria contain a large variety of fatty acids which are apo roxithromycin 300mg tablets comparison used for the biosynthesis of several complex cell wall lipids that have been implicated in the ability of the organism to resist host defenses. An Expeditious and Greener Synthesis of 2-Aminoimidazoles in Deep Eutectic Solvents. pylori infection, no changes in MIF mRNA expression and MIF secretion could be detected. An auditory vigilance task (Pigache Attention Task, PAT) required a button-press to targets during four 5-minute subtests (slow diotic, fast diotic, slow dichotic, fast dichotic, analogous to four versions of the continuous performance test).

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We fluvin capsule filler reviewed the magnitude and impact of these conditions, and discuss pharmacotherapy as well as new drugs under investigation. In support of the validity of the Cluster A construct, dimensional representations of schizotypal, paranoid and schizoid PD are all modestly heritable and share a portion of their genetic and environmental risk factors. Furthermore, the TTV ORF3 gene generated two forms of proteins with a different phosphorylation state, similar to the HCV NS5A region, suggesting that TTV ORF3 protein has function(s) similar to phosphorylated viral proteins such as the HCV NS5A protein. PROSPERO (International Prospective Registry of Systematic Reviews) 23 December 2013, CRD42013006249. The simulation results showed that changes in solubility had minimal impact on Cmax and AUC0-t of investigated BCS class 1 and 3 drugs.

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The development of a Salience of Lifestyle Index (SLI) is described and studied in relation to concepts of blame for illness, education, house tenure, religious commitment, employment, health behaviours and social background. We conducted a prospective study to remoxy oxycontin dosage evaluate performance of diverse accepted treatments for NCS. The strongest weekly shift occurred in winter, which reached as high as a factor of 1.6 for two consecutive weeks. The extent of oxidation induced by the FeP catalyst in solutions of phenolic monomers was followed in the presence of an oxygen donor such as hydrogen peroxide or dissolved oxygen under daylight radiation. From July 2009 to October 2010 we performed 238 diagnostic and operative hysteroscopic office-based procedures.

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The natural history of vaginal malignant melanoma differs from that of the skin with a more aggressive behaviour. We have used this model to study the impact of a primary hepatocyte mitogen, triiodothyronine (T3) on the liver regenerating by the recruitment of oval/progenitor cells. New genetic approaches to the diagnosis of childhood renal failure are becoming mainstream pregnancy ranitidine tablets side and will hopefully improve patient management, avoid clinical misdiagnoses, reduce the need for invasive investigations, and allow screening of at-risk relatives. These data justify hepatic resection for HCC arising in non-cirrhotic, non-fibrotic liver without underlying viral hepatitis. High frequency of cultivable human subgroup F adenoviruses in stool samples from a paediatric population admitted to hospital with acute gastroenteritis.

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In our cohort, young gay men in a relationship do not appear less likely to engage in risky sex with casual partners than men with casual partners only. The most prognostically dangerous are multiple abnormal chords of left ventricle, which can be a sign of serious hereditary disease - a left ventricular non-compaction. We have produced transgenic mice that ectopically express the transcriptional repressor Snail socalm baby name in heart. The degree of taxonomic diversity is influenced by modes of dispersal and potential biotic interactions. Due to the toxicity of PAs present in this medicinal plant, the regulations on PAs of Senecio scandens were varied among different countries and regions.

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Recto-vesical and recto-vesico-vaginal fistulae caused by radiotherapy for carcinoma of the uterine cervix. Particular attention should be paid to decrease relevant risk factors to improve the prognosis. In particular, the limited field trimol d s trimethoprim dosage of view and stroboscopic nature of the images can lead to many distortions from laryngeal imaging. Randomized controlled trials comparing operative and non-operative treatment for 3- and 4-part proximal humeral fractures were included.

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Tissue gene expression analysis using arrayed normalized cDNA libraries. Vocalization development has not been studied thoroughly in infants with early-identified hearing loss who receive hearing aids does azithromycin cure gonorrhea and chlamydia in the 1st year of life. These observations account for the specific binding of intestinal phosphatase when the dye is used as a ligand in affinity chromatography.