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OLIG2 is a recently identified transcription factor involved in the specification of cells in the oligodendroglial lineage. Smoking prevalence is particularly high amongst more deprived social groups. However, the genome-wide identification, tissue-specificity and functional implications of Apobec-1-mediated C-to-U RNA editing remain incompletely explored. Under peroxidation (H(2)O(2) of 300 micromol/L), the cytoskeleton remodeled at intercellular junctions, and changed over the meshwork structures into a dense bundle, that redistributed the stress.

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Assessment of lesion targeting is being studied in detail in an expansion cohort. The fat halo sign in the small intestine: diagnostic implications? In this paper we describe the development of a new model system and its application to drug delivery assessment. The data show that the protein displays a typical beta-jelly-roll fold. It has been claimed that the NHS has socialist principles, and represents an island of socialism in a capitalist sea.

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Successful use of anti-CD20 monoclonal antibody (rituximab) for ABO-incompatible living-related liver transplantation. Traditional single-point laser scanning confocal microscopy (LSCM) is generally limited by both the relatively slow speed at which it can acquire optical sections by serial raster scanning (a few Hz) and the higher potential for phototoxicity. Women aged 25-60 attending for a new screening round: 22 466 were assigned to the conventional arm and 22 708 were assigned to the experimental arm. A calcium ionophore-induced secretion in rabbit lacrimal gland in vivo.

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Tularemia is a zoonotic disease that occurs in the Northern Hemisphere caused by the gammabacterium Francisella tularensis. Occasionally, however, it may be difficult to distinguish an extratesticular process adherent to the testis from an intratesticular mass on the basis of US findings. The complex technology of producing rickettsial diagnostic immunoglobulin preparations and comparative technico-economic indices

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Anaerobic and aerobic growth of purple bacteria (Athiorhodaceae) in chemically defined media. The effect of technology on the indications for cataract surgery. Comparison of soil solution speciation and diffusive gradients in thin-films measurement as an indicator of copper bioavailability to plants.

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PD1 positivity, high Treg number, and EBV infection all predicted poor overall survival (OS) by univariate analysis. Observational study carried out, in 5 teaching hospitals, in northern Spain of patients admitted with CAP between March 1,1998 and March 1,1999 (baseline period), and between March 1, 2000 and September 30, 2001 (follow-up period). The differences with respect to the existence and/or relative strengths of subcortical connections of the examined auditory cortical fields suggest a somewhat different function of each of these fields in auditory processing.

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Restoration of normal anatomy was achieved after correct diagnosis and a two-step operation procedure. An analysis of prVEPs recorded after stimulation of different macular zones showed that the 3 degrees central area and the perifoveal zone contributed differently to the 13 degrees response or macular response.

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Association of MDM2 T309G and p53 Arg72Pro polymorphisms and gastroesophageal reflux disease with survival in esophageal adenocarcinoma. Contemporary patients had significantly prolonged survival and slower disease progression compared with patients from the historical group. Thus, our results suggest functional linkage of H3 and H4 acetylation in specific regions of the OC promoter to chromatin remodeling that accompanies tissue-specific transcriptional activation and vitamin D enhancement of OC gene expression. Diffusion maps obtained in vivo were close to those for uniform sets whatever the acquisition time was. The action of these efflux transporters at the BBB may be reflected in the clinic as the minimal effectiveness of drugs targeted at CNS disorders, including HIV dementia, epilepsy, CNS-based pain, meningitis and brain cancers.

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Marked racial differences and the consistently low prevalence rates amongst Malays are noted. Acitretin is an older, oral, non-immunosuppressive medication for the treatment of psoriasis. Supported by model simulations, we show the dynamics of opponent interactions between mutual inhibition and adaptation. All AFHs for the men and only TAFH for the women were significantly shorter for the Shona than for the whites. The congener profiles of PCDD/Fs indicated that the principal contamination source was the production of pentachlorophenol (PCP) or PCP-Na in this area.

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A total of 81 patients with transitional cell carcinoma of the bladder underwent fresh tissue biopsies directly transferred into RNALater and stored at room temperature or at 4 degrees C for increasing time intervals until RNA processing. Clinician-scientists will soon be able to extract an object, such as the heart, from the body electronically for the purpose of anatomic, functional, and histologic analysis without adverse effect on the patient. As heart surgery becomes increasingly focused on minimally invasive techniques, it has become apparent that conventional techniques of anastomosis will need to be severely altered or abandoned. Fibreoptic intubation using three airway conduits in a manikin: the effect of operator experience.

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Result of investigation of plasticity and reactivity of the epithelium and muscle tissues Although there are many different positron radionuclides for imaging diverse myocardial behavior, three radionuclides have reached accepted clinical utility. The importance of the assay to the P nutrition of soil fungi is considered based on the evidence currently available including the consistency of methodological approach. Before ALND is completely abandoned, these trials must be completed so that the role of SLND in the management of all patients with early breast cancer is fully defined.

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In contrast, in Experiment 1b, rats trained to escape shock by performing a longer duration inactive response were more impaired on the subsequent escape task than their inescapably shocked counterparts. tropicalis were recovered from the biphasic system (P less than 0.001).

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During a 5-year period, data from two academic endocrine surgical practices were retrospectively reviewed for patients having an operation for primary hyperparathyroidism. Measuring quality of care in patients with multiple clinical conditions: summary of a conference conducted by the Society of General Internal Medicine.

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Coronaro- and ventriculography, echocardiography (sectoral scanning), the computer-assisted treadmill exercise test were performed in all the patients. Problems arise if participants modify their gait patterns to ensure contact with the device. The Days and Nights of Zoo Elephants: Using Epidemiology to Better Understand Stereotypic Behavior of African Elephants (Loxodonta africana) and Asian Elephants (Elephas maximus) in North American Zoos.

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Analysis of sodium dodecyl sulfate-polyacrylamide gel electrophoresis-separated and eluted fractions of lysates from the recombinant HB101(pRTS47B4.3) demonstrated that the fractions containing the 47-kDa protein as well as those containing proteins less than 18 kDa were stimulatory. Regulation of the expression of Th17 cells and regulatory T cells by IL-27 in patients with unexplained early recurrent miscarriage.

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First, pedicle screw instrumentation obviates the need to place instrumentation within the spinal canal with its inherent risk of neurologic injury. The two sets of antibodies gave slightly different results that might be ascribed to the different epitopes recognized by the antisera.

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These data suggest that increased Fas expression on the cell surface might be a key event in the pathogenesis of autoimmune orchitis, by inducing a leakage of the blood-tubular barrier as a consequence of Sertoli cell apoptosis. The mouse serves as an important model for insulin-like (IGF)-related research. The purpose of this study is to analyze the relationship between the expression patterns of such immediate early genes and the cellular responses in the intestinal epithelial cells (IECs) after I/R stress. The individual treatment regimen with the most appropriate agent concerning efficacy and side effects has to be selected by the treating physician. Smoking reduction was defined as a decrease in mean daily tobacco consumption of 10 g or more.

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Phonon anomalies due to collective stripe modes in high T(c) cuprates. Severe torsional strain upon the bound substrate forces a distorted boat(2,5) B conformation for the glucosyl residue bound at subsite -1, which facilitates the formation of an oxocarbenium ion intermediate and might favor the breakage of the sugar ring concomitant with catalysis.

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Influence of hormone replacement therapy and aerobic exercise training on oxygen uptake kinetics in postmenopausal women. Vaccination of calves using the BRSV nucleocapsid protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects the lungs against BRSV replication and pathology. Consumer-directed care is currently being embraced within Australia and internationally as a means of promoting autonomy and choice in the delivery of health and aged care services.

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Daily administration of 1-25 mg cortisone acetate did not affect dietary intake, which remained the same as in saline (9 g sodium chloride/l)-injected controls. To ensure that your software optimizes your practice management systems, design systems that allow you and your team to achieve your goals and provide high levels of quality dentistry and customer service to your patients. Digoxigenin-in situ hybridization showed spred-2 mRNA-expressing cells were mainly seen in the proliferative zones such as the olfactory bulb, telencephalon, optic tectum, cerebellum, and the dorsal and ventral hypothalamus, and most of which were neuronal cells.

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Chemo- and regioselective functionalization of uracil derivatives. The major known hormonal functions of the kidney influence blood pressure, calcium metabolism, and red blood cell production. Histological scores and morphometrical measurements also showed the same results quantitively. Information was collected on diagnosis, staging, referrals, and treatment.

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Photodegradation of benzydamine: phototoxicity of an isolated photoproduct on erythrocytes. Up to 35 mL of gel with the physical properties of Femglide (transparent and odorless) was acceptable to the majority of participants. Using a pure solution of horseradish peroxidase as a model protein, no loss in enzyme activity was observed. The membranes could be reused a number of times without significant loss of urease activity.

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Comparative study between partial and complete pathological response. In this prospective study, C-reactive protein (CRP), fibrinogen, factor VIIIc, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha) levels were measured on admission, at discharge, and three and six months post-discharge in 40 patients with non-ST-segment elevation ACS (NSTE-ACS) and 40 healthy subjects. From 4 to 8 days postlesion (dpl) SNpR neurons ipsilateral to the lesion showed marked cytosolic accumulation of full length APP. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in combination with cytopathology is the optimal method for diagnosis and staging of pancreatic ductal adenocarcinoma (PDAC) and other pancreatic lesions.

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VirR has a positive effect on P(orf5) activity, whereas the response regulator encoded by orf8 is not involved in regulating transcription of the virR operon. Efficacy and safety of patient-controlled opioid analgesia for acute postoperative pain. Prospective studies are warranted to further validate our findings. The first step has been investigated in previous studies that showed that a substantial fraction of PCBs and lindane is mobilized from soil during artificial digestion.

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Streptomyces mobaraensis NRRL B-3729, Streptomyces paucisporogenes ATCC 12596 and Streptomyces platensis NRRL 2364 strains were screened for extracellular TGase production in SSF on different substrates. Spin lattice models predict that an infinite one-dimensional linear chain with short-range magnetic interactions spontaneously breaks up into segments with different orientation of the magnetization, thereby prohibiting long-range ferromagnetic order at a finite temperature. Our study is the first to describe BT management of spasticity in Tunisian children. Both form I and II ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) genes were detected in Thiobacillus intermedius by heterologous hybridization using specific probes from Anacystis nidulans and Rhodobacter sphaeroides, respectively.

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To determine whether atrial fibrillation (AF) in stroke-free patients is associated with impaired cognition and structural abnormalities of the brain. In the present study, we have investigated whether the group III mGluR subtypes mGluR4 and mGluR8 are expressed in MS lesions at various stages of evolution. In situ hybridization of the pituitary showed that while GPA2 is expressed in the anterior lobe, GPB5 is not detected in any of the lobes. Chromosomal translocations of the MLL gene are the result of illegitimate recombination events in hematopoietic stem or precursor cells, strictly associated with the onset of highly malignant leukemic diseases.

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Characterization of bovine neutrophil gelatinase-associated lipocalin. After two-week treatment, pathological changes of psoriasis-like models were observed by HE staining, and the difference in VEGF and PCNA expression levels among different groups was observed by immunohistochemical staining. The specimen was mounted in a testing machine built on a video stereomicroscope. A new method to determine ventricular volumes of the heart post mortem was developed.

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Characterizing alterations in executive functioning across distinct subtypes of cortical and subcortical dementia. Number of mitotic figures in microscopic picture of nephroblastoma histologic types--estimation of the value of the oldest known prognostic factor.

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In contrast, 1 microM SB203580 did not affect AII-stimulated TOH phosphorylation, but fully inhibited heat shock protein 27 (HSP27) phosphorylation produced by AII. Fragmentation of phosphopeptides by atmospheric pressure MALDI and ESI/Ion trap mass spectrometry. Lumboperitoneal (LP) shunts have traditionally been used in patients with IIH due to a frequently undersized ventricular system. Other cases were solitary, with evidence for secondary involvement of S. Major depressive disorder (MDD) is a chronic disease whose neurological basis and pathophysiology remain poorly understood.

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Minority stress is the most frequently hypothesized risk factor for the increased rates of adverse behavioral and mental health outcomes among sexual minorities. Inactivation of Chinese hamster V79 cells in vitro by a temperature elevation to 43 degrees C and with Couette shear flow was investigated.

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Bladder replacement with an isolated bowel segment is feasible in properly selected patients. A Lewis Acid Catalyst Anchored on Silica Grafted with Quaternary Alkylammonium Chloride Moieties T.M.J.

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While preparation of gamma-CEHC-d(2) has already been described, here we report the first synthesis of alpha-CEHC-d(3) together with alpha-tocopheronolactone-d(3), its oxidation product. Therefore, we hypothesized that H-2545 could reduce the doxorubicin-induced acute deterioration of cardiac function. Descriptions of the initial formation, development, and maturation of the incisive fissure and the transverse palatine suture, in combination with a comparison between the suture systems, were not found in the literature.

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Fundamental movement skills and children with attention-deficit hyperactivity disorder: peer comparisons and stimulant effects. These results, coupled with the observation that the proportion of coherently moving dots required to produce positional shifts correlated well with global motion thresholds measured for the same dot configurations, suggests that visual processes which underlie motion-dependent positional shifts are based at least in part on cooperative interactions of the type implicated in global motion. Using small interfering RNA, we have demonstrated that PPARdelta expression is required for the effect of GW501516 on the intracellular accumulation of fatty acids. Sites of neuronal excitation by epiretinal electrical stimulation.

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Case study of ecstatic meditation: fMRI and EEG evidence of self-stimulating a reward system. We present participant feedback on the course content, and potential future directions for course development. The antioxidant system is very less in brain tissue and is very much susceptible to hypoxic stress. Within-child associations between family income and externalizing and internalizing problems.

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We demonstrated that the Mn(II)-oxidizing activity in co-culture was most likely induced via contact-dependent interactions. uPAR and Serin protease were overexpressed, and E2A and IGF1R were underexpressed in both metastatic sublines. Thirty-one boys aged 12-15 y participated in 3-wk metabolic balance studies testing a range (700-2100 mg/d) of calcium intakes in a crossover study design with a 2-wk washout period.

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An instrument for the study of vascular factors in the physiology and pathology of the human mammary gland. Women were asked whether their symptoms resolved completely, improved, remained unchanged or deteriorated. Our data lends credence to the notion that the effects of long-acting nitrates in daily life and the effects measured during stress testing may involve different mechanisms.