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To evaluate objectively the visual fields of patients with pediatric epilepsy who are uncooperative with perimetry and in whom postoperative visual field deficits are expected, the authors investigated the usefulness of the multifocal visual evoked potential (VEP) method. Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer. Non-islet cell tumor hypoglycemia syndrome is caused by the tumor producing insulin-like growth factor II, causing hypoglycemia.

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Single chain fragments, Fab fragments, and two diabodies were purified and compared in their CEA-binding properties with the parent IgG using surface plasmon resonance detection. Effect of aerosol therapy with cyclopheron in patients with chronic rhinitis They were interviewed in detail, all patients and 16 relatives (including all symptomatic cases) were examined neurologically and a multiple sleep latency test and HLA-typing were done.

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PARTICIPANT AND INTERVENTIONS: Male Sprague-Dawley rats were implanted with electroencephalogram electrodes, a thermistor, and an intracerebroventricular guide cannula. The enzyme IIIglc-like domain of Bacillus subtilis IIglc (IIIglc, 162 residues, 17.4 kDa) has been cloned and overexpressed in Escherichia coli. These could be used to calculate confidence intervals for all reported titers and allow benchmarking of assay performance. Sodium perxenate in alkaline solutions is reduced in a single step to xenon at the dropping-mercury electrode. Chlamydomonas is therefore the organism of choice for elucidating detailed functions of the hundreds of genes involved in plant photosynthesis.

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The study of medicinal plants for treatment of periodontitis is of great value to establish their efficacy as sources of new antimicrobial drugs. Having these pillars as bases, we promoted the participation of the population concerning Chagas disease, and a Community Action Group was formed with young people, adult men and women, and social leaders. Vomeronasal organ lesion disrupts social odor recognition, behaviors and fitness in golden hamsters.

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Colonic secretion of oxalate is stimulated in rat models exhibiting hyperoxalemia suggesting a contribution of this extrarenal pathway to regulation of oxalate mass balance in clinical conditions manifesting hyperoxalemia. Nurses provide health services to IDPs as staff of non-governmental organizations (NGO).

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Significant predictors of patient self-rated QOL were patient symptoms of depressed mood and functional ability at clinic day, and symptoms of depressed mood and clinic day QOL at one year. Formalin-induced oxidative stress in the cardiac tissue was more considerable. The acknowledgement of differing belief systems is important for high quality, integrated care.

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An increasing prevalence since 2010 of Serratia marcescens harbouring the Ambler class A carbapenemase SME prompted us to further characterize these isolates. the nitrite route prevailed and also filamentous bulking was provoked in the SBR system.

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Calcium depletion enhances nectin-1 expression and herpes oncolytic therapy of squamous cell carcinoma. We propose that bacteriophage FC3-9 efficiently infects bacterial cells grown at low pH or low temperature because its enzymatic activity on the capsule makes lipopolysaccharide available to this phage. Nitric oxide modulation of neurally induced proximal tubular fluid reabsorption in the rat. Polarization patterns and vectorial defects in type-II optical parametric oscillators. Since the end of the 1980s, the incidence of plague in Madagascar has increased in both rural and urban areas, because of multiple socioeconomic and environmental factors.

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Improving our global diet by working with the food industry is a fairly complex task. The study is aimed to investigate the process of endothelial repair related to endothelial progenitor cells (EPC) in systemic sclerosis (SS), and analyze the role of EPC abnormalities in endothelial dysfunction and impaired angiogenesis. We have now identified causative mutations in 15 families, which allows us to clinically define this entity by onset between 10 and 22 years, cerebellar atrophy, axonal sensorimotor neuropathy, oculomotor apraxia and elevated alpha-fetoprotein (AFP).

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The role of ifosfamide in cytoreduction, stem cell mobilization and high-dose therapy in relapsed/refractory malignant lymphomas. Notably, the Zn and Cu concentrations in the liver tended to decrease with increasing body length. Here we describe a mathematical model that demonstrates that CIL alone is sufficient to produce coherent, collective cell migration. Testis development is a tightly regulated process that requires an efficient and coordinated spatiotemporal action of many factors, and it has been shown that several genes involved in gonadal development exert a dosage effect. The standard drug combinations were first vincristine, adriamycin, and cyclophosphamide (VAC) and then, from the early 1980s, etoposide-platinum combinations.

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The Maryland Senior Olympic Games is a model program that offers incentives to the ever-increasing number of older Americans who exercise regularly and want to compete. Lumen dimensions and vessel morphology were assessed with intravascular ultrasonography. Indications for this examination include the evaluation of incontinence, anal fistulas, anal carcinoma and anal pain.

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The N-terminal catalytic domain is more stable and less prone to aggregate than full-length enzyme and is thus potentially more suitable for structure determination by X-ray crystallography. In the present review, history, current clinical use as well as future perspectives of As2O3 therapy in both hematologic and solid malignancies are discussed, with special emphasis being put on the potential future role of As2O3 in the treatment of non-APL tumors. Each lesion was subjected to both clinical and dermoscopic evaluation before surgery.

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New oxamato-bridged trinuclear Cu(II)-Cu(II)-Cu(II) complexes with hydrogen-bond supramolecular structures: synthesis and magneto-structural studies. Changing patterns of consultation in general practice: fourth national morbidity study, 1991-1992. Estimate the frequency of failure to follow the French consensus guidelines for elective induction, and assess how failure affects the rate of cesarean delivery. The mesoporous carbon nanofiber arrays that stand on carbon-gold double-layer current collectors are synthesized by self-assembly of a PS-b-PEO copolymer and resol in AAO templates for a high-power micro-supercapacitor at high current densities.

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The alkylating agent MNNG is an environmental carcinogen that causes DNA lesions leading to cell death. VF occurred in the night unrelated to myocardial ischemia or myocarditis. Unconsciousness in humans has probably been occurring since before recorded history.

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The article analyses andrological aspects of Hebrew medicine and legislation. This suggests that inaccuracy of responding is characteristic of children having (a familial risk for) ADHD. The method could be efficiently used to extract the HRV from an ECG measured for healthy subjects performing an exercise in which the HRV increases linearly with time, and for subjects with respiratory and cardiac problems.

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Intracortical injection of iron ions has been used as a model of posttraumatic epilepsy. These ubiquitous molecules are synthesized by terpene synthases via complex carbocationic reactions, incorporating highly reactive intermediates. Frequently, abiraterone and enzalutamide are used prior to chemotherapy in mCRPC, given the more favorable safety profiles. Motion-based Simon effects occurred when the displays could be interpreted as an upright human walker, showing that a high-level representation of motion direction mediated the effects. The distribution of this receptor mRNA is consistent with a role for the Y5 receptor in food intake and also suggests involvement in other processes mediated by NPY.

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Caution on the interpretation of plasma fatty acid composition as a proxy marker for SCD1 activity: particular implications for using the 16:1/16:0 ratio in QTL studies involving hyperlipidemic patients. Lenses manufactured by lathe-cutting exhibit notable higher values, so that they could be easily distinguished from others.

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Targeted penetration and release of ascorbic acid by the use of multiple phase technology. Does prehospital fluid administration impact core body temperature and coagulation functions in combat casualties? Periodontal mechanical treatment was carried out in both groups. The patients were evaluated with regard to pain, postoperative function, union of the allograft (osteosynthesis), and the prevalence of local recurrence. We obtained mean ciprofloxacin levels of 0.53 microgram/ml in aqueous humor, 0.51 microgram/ml in vitreous, and 0.71 microgram/ml in subretinal fluid.

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During four years of follow-up, we documented 667 cases of coronary disease. In the context of an ongoing study we looked at 1-year symptomatic outcome of 37 outpatients fulfilling DSM-III-R criteria for bulimia nervosa in relation to a variety of measures at first assessment. Current options for ARMD prevention and treatment are limited due to an incomplete understanding of disease etiopathogenesis. Initial vertebral separation was greatest in those specimens with wide disc spaces and least where there was evidence of disc degeneration.

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This result might be owing to the dominant side of the hand/foot and hemisphere lateralization. Emergency Department of the University Hospital, Zurich, Switzerland.

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The laryngeal assessment of 30 patients was performed, and the presence of VCP was inferred while the following 15 patients by endoscopy before extubation after performing consecutive radical esophagectomy in 45 esophageal cancer patients. A DLI was associated with an almost two-fold increase in the odds of readmission. An oro-antral fistula was often created by the extraction of a molar to drain the infected maxillary sinus daily.

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Percutaneous coronary revascularization using drug eluting stents has been a major revolution during the last five years for symptomatic relief of angina in symptomatic CAD and can be applied to large subsets of patients. The extra costs of monitoring patients treated with oral anticoagulants were limited and play no role in the decision for treatment. Crozer-Keystone puts its money where it sees its future--in the community. The permeation of ions and small metabolites through gap junction channels or hemichannels confers a crucial role to these proteins in intercellular communication and in maintaining tissue homeostasis. Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors.

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Contrast harmonic ultrasound of spontaneous liver nodules in 32 dogs. Detailed morphological and physiological studies are necessary as a basis for understanding normal, near normal and abnormal conditions of the middle ear cleft. The case is presented of a 65-year-old man who developed a giant antrochoanal polyp which blocked the right maxillary sinus, nasal cavity, nasopharynx, oropharynx and hypopharynx.

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These data suggest that the decrease in DHEA and DHEA-S concentrations together with the high F levels that occur in patients with type 2 diabetes mellitus is associated with low 17,20-lyase and high 17-hydroxylase activity in the adrenal steroidogenic enzymes. The immunoglobulin-binding protein binds to the Fc-fragments of the immunoglobulins and binding depends on the presence of calcium ions.

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Furthermore, breakdown of these coatings within the human body can cause release of the anti-microbial drugs in an uncontrolled or unpredictable fashion. Among heme-thiolate proteins nitric oxide reductase (P450nor) is unique since it catalyzes the conversion to dinitrogen oxide as a reductive process. Steal syndrome secondary to coronary artery fistulae associated with giant aneurysm. Further assessment with the Farnsworth-Munsell D-15 panel was performed for those who failed the Ishihara test.

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In routine clinical treatments, microleakage following with secondary caries usually occurs due to the discrepancy in physico-chemical property between filled materials and tooth. 32 feet in 27 adults, seen at The Johns Hopkins Hospital Foot and Ankle Clinic from 1993-1998, with the diagnosis of tarsal coalition were retrospectively reviewed. We further revealed that long-term depression (LTD) of parallel fiber-Purkinje cell synapses plays a critical role in both the day- and week-long adaptations.

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Some MED targets encode transcription factors related to those that regulate mesendoderm development in other phyla, supporting the existence of an ancient metazoan mesendoderm gene regulatory network. The goal of the present studies was to test the effects of photoperiod on aggression in male Siberian hamsters (Phodopus sungorus) and to determine the role of T in mediating photoperiodic changes in aggression. The role of individual decisions on the basis of secure scientific knowledge gets more and more dominating with emphasis placed on the assessment of functional achievements. It may be diagnosed as a result of symptoms such as difficulty in breathing, pain on sneezing or blowing the nose or may remain asymptomatic. Whether higher levels of physical activity can counteract the elevated risk of death associated with adiposity is controversial.

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Biopsies from normal areas of the bladder from an age-matched control group of patients with transitional cell carcinoma of the bladder were stained similarly. In 2003, residents of the District of Columbia (DC) experienced an abrupt rise in lead levels in drinking water, which followed a change in water-disinfection treatment in 2001 and which was attributed to consequent changes in water chemistry and corrosivity. Thus, both the spatial distribution and mechanism of mitochondrial quality control in vivo differ substantially from those observed in vitro. In contrast, the mechanisms for punishment-avoiding behaviors are less well known. Pharmacokinetics and safety of ebastine in healthy subjects and patients with renal impairment.

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A new immunoglobulin isotype in fish expressed in early development. Reducing atrial tachycardia and atrial fibrillation episodes with a prevention and treatment device and tailored treatment. Human immunodeficiency virus type 1 (HIV-1) infection of simian cells is restricted at an early postentry step by host factors whose mechanism of action is unclear. The scope of the method is broad with respect to different substituents (alkyl, aryl, metallocenyl, and other substituents as well as their combinations are tolerated), and all steps proceeded with sensible yields.

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Acute appendicitis is common, frequently atypical, challenging, and still associated with significant morbidity. Comparison of experts experience in the given field is another indispensable part leading to optimisation and improvement of processes, and optimally to implementation of standards. Gastric fundus perforations (20-mm diameter) were created by an endoscopic needle-knife in six dogs. During that time the epithelium may misinvaginate into double lamellas and such double lamellas formed by the inferior turbinate may become persistent.

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There is considerable controversy regarding the diagnosis of Acute Kidney Injury (AKI), and there are over 30 different definitions. The Japanese Red Cross (JRC) carries out nucleic acid amplification testing (NAT) for hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus-1 (HIV-1) by using a multiplex (MPX) reagent. Treatment with progesterone or oestradiol-17 beta after unilateral ovariectomy did not inhibit the increase in plasma FSH levels, while the increase in plasma concentrations of FSH after surgery was completely inhibited by injecting inhibin (porcine follicular fluid). Antibiotics and sulfa drugs in the treatment of acute peritonitis caused by appendicitis: clinical-statistical contribution

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Throughout much of prehistory, humans practiced a hunting and gathering subsistence strategy. Polar lipid or whole cell ester-linked fatty acids are generally analyzed by gas chromatography-mass spectroscopy. Parameters of thermoelectric cooling devices in conditions of variable temperatures of the heat-exchange media This paper proposes a collaborative data aggregation in emerging sensor networks using a bio-level Voronoi diagram, which is an energy-efficient data aggregation protocol that integrates topology control, Multiple Access Control (MAC) and routing. The promise of interrupting the aggregation of platelets in the setting of unstable plaques on a chronic basis had led to the evaluation of several oral agents for longer-term administration.

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Partners in Caring and Community: service-learning in nursing education. We have fabricated, to our knowledge, the first rectangular cross-section multicore fiber with eight cores arranged in a line. (2) To determine the feasibility of further trials in this population in terms of magnitude of comparative clinical effect, rate of recruitment, and loss to follow up.

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Rheumatoid arthritis aggravated by pregnancy and controlled by cortisone. To clarify the risk factors and develop a refined risk-stratification model to help in the appropriate selection of docetaxel chemotherapy in patients with castration-resistant prostate cancer. In this report, we identify a 30 bp DNA element required for mediating the activation of CRYAB by brahma-related gene 1 (BRG1). Moreover, this hierarchically staggered nanostructure provides an optimized microenvironment to improve bone regeneration by instructing host cells. Treatment of alcohol use disorders in patients with liver disease.

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We conclude that mortality in spina bifida is a large concern, and individuals living with the defect require improved clinical care for lethal medical complications. The objective of this study was to investigate the responsiveness and the ability to provide information about diabetes-specific associations with HRQOL, of two generic instruments, in comparison with two diabetes-specific instruments, in patients with T1DM. Bone marrow cells migrate to the heart and skeletal muscle and participate in tissue repair after Trypanosoma cruzi infection in mice. Streptavidin (SA)-installed ytterbium (Yb) and Er ion-codoped Y2O3 (Y2O3:Yb,Er) NPs (UNP2s) were prepared by the coimmobilization of PEG- b-PAAc and streptavidin.

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Regulatory role of OX22high T cells in mercury-induced autoimmunity in the brown Norway rat. Apical orientation of the microtubule organizing center and associated gamma-tubulin during the polarization of the retinal pigment epithelium in vivo. D53 contains two putative helical regions, one of which includes a large coiled-coil domain involved in the interaction with Sb2 in vitro. The aim of this study was to analyze the factors affecting the outcomes after surgical treatment of acetabular fractures. Forecasting the global shortage of physicians: an economic- and needs-based approach.

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3D T2-weighted MRI has been increasingly utilized for pelvic applications, including imaging of rectal cancer, prostate cancer, anorectal fistulas and the female pelvis. Four different patterns of pulmonary venous flow and mitral regurgitation were examined.