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Klopidogrel (Clopidogrel)

Klopidogrel reduces the stickiness of platelets, and this helps prevent the platelets from sticking to the inside of an artery and forming a thrombus. This reduces the risk of you having a heart attack or stroke. In your blood there are 'sticky' cells called platelets. When you cut yourself, the platelets stick to each other (clot) to seal the wound. Sometimes platelets stick to each other inside an artery - this is called a thrombus. A thrombus can block a blood vessel, and this is often the cause of a stroke or heart attack. This is more likely to happen if the walls of your arteries have areas which have become thickened with fat deposits, or if you have a fast irregular heartbeat. If a thrombus forms in a blood vessel around your heart, this reduces the flow of blood to your heart. The term acute coronary syndrome (ACS) covers a range of disorders that are caused by this underlying problem. If you have been prescribed Klopidogrel because you have ACS, it may mean that you have had a heart attack, or that you have angina pain that is not well controlled.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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Pharmacogenetic influences on treatment response and toxicity in colorectal cancer. The area of the frozen allograft did not increase between 2 and 4 months. The tumorigenicity of HepG(2) cells transduced with Ad-multigenes was detected.

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Is laparoscopic injection of 2-octyl-cyanoacrylate tissue adhesive (Dermabond: Db) into the inguinal hernia sac (IHS) effective for inguinal hernia repair? The year 2012 in the European Heart Journal-Cardiovascular Imaging. By contrast, stress does appear to play a role in the control of alcohol ingestion by adolescents.

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Protective effect of 20-hydroxyeicosatetraenoic acid (20-HETE) on glomerular protein permeability barrier. Relationships between self-assessment skills, test performance, and demographic variables in psychiatry residents. Severe hypoglycaemia and glycaemic control in Type 1 diabetes: meta-analysis of multiple daily insulin injections compared with continuous subcutaneous insulin infusion.

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Integrated delivery systems are often seen as the answer to the question of how to deliver high quality health services to a defined population at the lowest possible cost. Results show that the length of non-OE scales nearly isometrically with cranial length, while OE is more negatively allometric. Circadian variation in vascular tone and its relation to alpha-sympathetic vasoconstrictor activity.

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Psychological interventions are needed to treat PTSD and PTSD/SUD in HIV-positive individuals, and reduce the negative impact of these conditions on health outcomes. The RNA component (TR) serves as template for telomerase reverse transcriptase (TERT) for generating telomere repeats. These transient population effects are applicable in any multiphoton resonant transition. Starvation ketoacidosis: a cause of severe anion gap metabolic acidosis in pregnancy.

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HOXA11 and MMP2 gene expression in uterosacral ligaments of women with pelvic organ prolapse. However, basal levels of receptor kinase activity were significantly elevated by thiol-biotinylation. Toxicity was assessed on imaging (global hepatic damages (GHD), overall biliary injuries, biliary cast, bile duct dilatation, intrahepatic biloma, portal thrombosis), and clinico-biological follow-ups.

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The varicella shortage was associated with an immediate drop in the 24-month varicella immunizations rate but rebounded quickly to above pre-shortage rates. Thus, acetylcholine, whose presence in sweat gland innervation is retrogradely specified by developmental interactions with the target tissue, in turn plays an important role in inducing and maintaining target tissue responsiveness through muscarinic receptor activation. Excito-repellency effect of deltamethrin on triatomines under laboratory conditions. Measuring work organization exposure over the life course with a job-exposure matrix. Cross-country comparisons are made and graphical surfaces are analyzed in order to interpret the results.

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The aim of the present study was to determine the effects of CD134 monoclonal antibody (MAb) on expression and hemolysis activities of perforin and its mechanisms. Endometriosis with urinary involvement associated with hepatic hemangioma Moreover, reducing nmr function in the absence of pannier further aggravates the deficit in cardiac mesoderm specification. Retrospective analysis of 3333 singleton live births after 36 completed weeks of pregnancy.

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Obstetricians seem to be overstating the evidence in major placenta praevia. Clinical characteristics and outcomes of patients with hypertrophic cardiomyopathy with latent obstruction.

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In two of the eight index cases, we identified novel heterozygous missense mutations in MYH2, one in each case: V970I and L1061V. Previous work suggested that the haplotype structure of the two genes is probably maintained by recombination suppression at the S locus. Smoke from antiasthmatic cigarettes of belladonna, hyoscyamus and stramonium and experimental asthma

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Transesophageal echocardiography and the intraoperative diagnosis of a right pulmonary artery aneurysm. Changes in B and T-cell subsets and NMO-IgG levels after immunoglobulins and rituximab treatment for an acute attack of neuromyelitis optica. The use of computerized axial tomography has revealed the true dimensions of these fractures, and the diagnosis of biplane and triplane fractures can now be made by standard radiography alone. These methods are including the regular perturbation method, the new development of the variational iteration method, and the homotopy decomposition method.

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Scientific expertise is applied at each phase of development to critically review the testing methods and results, and to establish and apply criteria for evaluating the agents for further development. Reciprocal expression of two candidate di-iron enzymes affecting photosystem I and light-harvesting complex accumulation. We reviewed the cases of 13 patients who underwent 15 surgical procedures for palmar midcarpal instability from 1981 to 1989.

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Major histocompatibility complex class I (MHCI) proteins present antigenic peptides for immune surveillance and play critical roles in nervous system development and plasticity. Although regular aerobic physical activity increases exercise capacity and plays a role in both primary and secondary prevention of a variety of chronic disorders, competitive physical exercise is associated with a significant increase of risk of sudden death in athletes, especially adolescents and young adults. To verify if the age is a risk factor for secondary headaches, regardless the time interval since the onset of the headache complaint. The liquid condensed domains adopt an elongated morphology in the presence of DNA, especially in the presence of calcium.

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A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions. We studied the disappearance of NPs from the epithelium by sequential lung retention and clearance and bronchoalveolar lavage (BAL) measurements in healthy adult Wistar Kyoto (WKY) rats at various times over 6 months after administration of a single 60- to 100-min intratracheal inhalation of iridium-192 ((192)Ir)-radiolabeled NPs. These results suggest long-term local intensive preoperative chemotherapy, including intra-arterial cisplatin and hyperthermic isolated regional perfusion, help control local tumor and allow for more conservative surgery. VLC appears to have no clinically beneficial effect on the oral mucosa compared with AP. The anteroposterior width of the velopharynx significantly increased when the mandible was advanced from RP to MAX67 and MAX.

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Successful treatment of a catheter-related right atrial thrombosis with recombinant tissue plasminogen activator and heparin. Promoter activities and TGFbeta induction were assayed through transient transfections in Smad4-negative human cancer cells and their stable Smad4-positive derivatives. Miners and smokers have high concentration of malonil dialdegide in blood. Patient safety and quality of care improvement goals unify caregivers in all types of healthcare provider organizations.

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Progression to advanced liver fibrosis in HIV-HCV-coinfected patients and prioritization of new hepatitis C therapies. A new drug, trimetrexate, and the standard second-line therapy, pentamidine, are both inferior to the standard first-line therapy, trimethoprim/sulfamethoxazole, as initial therapy for moderate to severe PCP. Such reduction occurred in both dendritic shaft and spine synapses.

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TB control strategies need to take into account reinfection as an important cause of recurrent TB. The expression of the observed TBK as a percentage of the expected value for a normal child, of the same weight and height, appears to be a useful index of the severity of the total body potassium deficit. Atopic dermatitis (AD) is a chronic inflammatory skin disease that is characterized by a defective skin barrier function. The reduction in filtering rate is the result of interference competition between two species and may be linked to the evolution of a mechanism for avoiding predation. Cost-effective and rapid platforms for the detection of changes in the global levels of methylation are of value for the investigation of the processes that regulate methylation.

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Anterior-posterior cerebral blood volume gradient in human subiculum. Heat shock protein 20 (HSPB6) regulates apoptosis in human hepatocellular carcinoma cells: Direct association with Bax. Four separate groups of birds received systemic exposure to either testosterone, estradiol, a combination of an anti-androgen and an inhibitor of estrogen synthesis, or nothing. The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology.

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Heparin and heparin-bound bFGF uptake and release were evaluated by (123)I radio-labelling. HSPS represent major immunodominant antigens in a wide spectrum of microbial pathogens. Indeed, these new therapies have demonstrated long-term improvement in patient outcome, a benefit not afforded by traditional therapeutics. How to fix the edge effect of catheter-based radiation therapy in stented arteries. Tissue inhibitor of metalloproteinases-3 moderates the proinflammatory status of macrophages.

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The major cause of hemodialysis vascular access dysfunction is venous stenosis as a result of neointimal hyperplasia. A method for inducing clathrate anabiosis of leukocytes was developed that preserved the cells for practical use in biology and medicine. Nonnarcotic analgesics, antidepressant, and estrogen/progestin were the three most common classifications of medications mentioned.

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Effect of early pregnancy on maternal regional cerebral blood flow. Excimer laser versus narrow-band UVB (311 nm) in the treatment of psoriasis vulgaris. The authors present a short review of the pertinent literature and report on their own neuropsychiatric findings following internal craniocerebral injuries, at the same time drawing attention to the necessity of psychological examination. We also found that the relative standard deviation of fluctuations in substitution rate is about a factor three smaller in mouse than in human. The interferon-induced transmembrane protein 3 (IFITM3) inhibits infection of multiple families of viruses in cell culture.

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OA represents an increasing threat to the quality of life of affected persons as well as for health resources expenditure. TNF-alpha up-regulation of CD44 expression was dependent on the activation of c-Jun NH(2)-terminal kinase (JNK) and this activation was accompanied by an increase in their invasive phenotype. This is the 10th in a series of articles exploring international trends in health science librarianship. Effects of the novel selective endothelin ET(A) receptor antagonist, SB 234551, on the cardiovascular responses to endotoxaemia in conscious rats. The possible implication of this finding is discussed in view of the proposed role of arrestin in the down-regulation of the enzymatic cascade of phototransduction.

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The reference population was delivering women from the source population with background exposure level. However, no systematic study of the immunity of Cyrtomium macrophyllum ethanol extracts (CM) has yet been reported.

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This work highlights the ability of both electroporation and the HIV-1 Gag plasmid to stimulate innate immunity for enhancing cancer DNA vaccine immunogenicity and demonstrates interesting tracks for the design of new translational genetic adjuvants to overcome the current limitations of DNA vaccines in finax tablet contents humans. We have investigated the ferroelectric polarization switching properties of trialkylbenzene-1,3,5-tricarboxamide (BTA), which is a model system for a large class of novel organic ferroelectric materials.

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Building successful coalitions for promoting advance levofloxacin antibiotic coverage for dog care planning. aCRT algorithm is safe and efficacious for CRT-indicated patients without permanent atrial fibrillation. Early serum sodium levels after aSAH can be considered as surrogate markers to predict outcome after aSAH irrespective to the occurrence of DCI. Photodynamic therapy (PDT) has emerged as a promising clinical modality for cancer therapy due to its ability to initiate an antitumor immune response. The potential responses in the sympathetic renal nerve (RN) and somatic lumbar nerve were recorded simultaneously.

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The described mechanisms are sufficient to explain the formation of the anterior and the posterior knirps expression, the posterior hunchback expression domain, and the lateral stripes of rhomboid expression and of other ventral neurogenic ectodermal genes. This prospective, single-center, single-arm study evaluated the technical feasibility and safety of EUS-guided biliary drainage using novel balloon catheters. The endurance of the erector spinae muscle was determined using a modified version of the isometric Sorensen fatigue test. We reported here a case of fungemia, which was diagnosed by a globular numeration: peripheral blood smears showed yeast cells, especially in the cytoplasm of neutrophils, with characteristic images of fungal phagocytosis. Dimensionality reduction is an important issue for numerous applications including moxypen forte 250 amoxicillin and alcohol biomedical images analysis and living system analysis.

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A nested reverse transcription-PCR (RT-PCR) assay was developed for qualitative analysis of the echovirus 30 VP1 fenered mg to g encoding sequence directly from cerebrospinal fluid. Indications and current limitations of artificial hibernation used in obstetric and gynecological practice

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