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Letop (Topiramate)
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Topiramate

Letop is a unique antiseizure medication that is used in treatment of partial and generalized seizures. Letop has been rarely associated with hepatic injury and largely when used in combination with other anticonvulsant medications. Letop is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Letop is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Salivary interleukin-6 and tumor necrosis factor alpha in patients with drug-induced xerostomia. Associations between CWP and most comorbidities are mediated by unmeasured genetic and family environmental factors in the general population. Transcatheter aortic valve implantation (TAVI) is an effective treatment for high-risk or inoperative patients with severe aortic stenosis. Efficient and stable gene expression in rabbit intervertebral disc cells transduced with a recombinant baculovirus vector. Randomized controlled trial of 464 sedentary, postmenopausal overweight or obese women whose body mass index ranged from 25.0 to 43.0 and whose systolic blood pressure ranged from 120.0 to 159.9 mm Hg.

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The procedures revealed an intestinal type gastric adenocarcinoma. Manganese presented in the intestine and stomach in the highest concentration. Highlights of the 6th Congress of the International Xenotransplantation Association, Chicago, 2001. Plasma sufentanil concentration after intranasal administration to paediatric outpatients.

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This algorithm has applications in various fields, including media art, digital signage, and encryption technology. Alterations of eye movement control in neurodegenerative movement disorders.

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To obtain a better insight into the possible role of vitreous body in proliferative vitreoretinopathy (PVR), we examined the influence of bovine vitreous body fractions separated by fast protein liquid chromatography (FPLC) on the growth of porcine retinal pigment epithelial (RPE) cells in vitro. Her clinical features included no adrenal crisis despite poor drug compliance, poor pubic hair development (Tanner stage 2), well-developed breasts (Tanner stage 5), and regular menstrual cycles. Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities. The aim of this study was to determine the contribution of the human major histocompatibility complex (HLA)-DQA1, -DQB1, and TNFalpha genes with simple nasal polyposis. The School Meals Planner Package supported the design of nutritious, locally sourced menus for the school feeding program in Ghana.

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Atlanto-occipital dislocation is rarely survivable, and delayed diagnosis can negatively affect long-term clinical outcome. Using Affymetrix DNA microarrays, we show here that the AREG gene was expressed by purified primary myeloma cells from 65 patients and that the expression was higher than in normal bone marrow (BM) plasma cells or plasmablastic cells.

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Maternal and child health findings were alarming with high rates of miscarriage and infant loss, with no traditional midwives to assist in pregnancy and delivery. The sequence of the 54 N-terminal amino acid residues has been determined by automated Edman degradation. Despite the great promise afforded by this technology, the ultimate benefit of applying transcriptional profiling in prospective clinical trials has yet to be realized because a number of practical impediments to this process exist. Fatty acids from lipids of marine organisms: molecular biodiversity, roles as biomarkers, biologically active compounds, and economical aspects.

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The present study was conducted to reveal the prevalence and electrophysiologic characteristics of the confluent inferior common PVs. The boundary conditions of the numerical model simulated a load on the incisors with a 15 mm mouth aperture. (18)F-FDG PET studies of obese patients represent an ongoing challenge, which requires patient-tailored solutions to avoid compromising image quality and risking higher radiation exposure to the technologists. After successful IATT, subsequent therapy can be tailored to the anatomic cause of thrombosis.

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Despite this high incidence the pathogenesis of fibroids is widely unsolved. SCS modifies the capacity of intrinsic cardiac neurons to generate activity. Nonoperative treatment of posterolateral knee injuries tends to yield poor results.

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Randox total antioxidant status, selenium, ferritin, transferrin, ceruloplasmin, tocopherol, and retinol levels were evaluated in blood samples obtained from 11 dark-skinned patients from the French West Indies (Isle of Martinique) with recent active lesions of vitiligo and from 11 age- and sex-matched healthy volunteers. Squamous metaplasia with decreased goblet cell density and increased nucleus-to-cytoplasm ratio occurred in anophthalmic conjunctival sockets but was not associated with particular aspects of prosthesis care. In this study, the authors applied to composite tissue allotransplantation what nature has developed for pregnancy, and examined the immunosuppressive effect of tryptophan metabolites in a model of hind limb transplantation. Remote cerebellar haemorrhage (RCH) is an unusual complication of supratentorial neurosurgical procedures. The data presented in this study indicate that the intake of patulin with apple derivatives is usually below the tolerable level of 0.4 microgram/kg bw/day, but since the patulin content in apples can vary considerably, the quality of fruits used in the production of apple derivatives should be strictly controlled in order not to exceed the safe limits.

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A comprehensive examination process, as described in part 1 of this series, can reveal underlying clinical findings that assist in the delivery of comprehensive physical therapy services for patients with TMD. Data were analysed using a grounded theory approach for sub-themes related to the pre-selected major themes of maternal HM production and infant HM consumption. Production of mutant dihydrofolate reductases of Lactobacillus casei for nuclear magnetic resonance spectroscopy. The prevalence of actinic keratoses was significantly associated with oil shale work after allowing for age, sun exposure, and other exposures.

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The sensitivity of cerebral monitoring methods for the detection of air emboli is not known. The influence of bone on dose distributions due to fast neutrons generated at the Naval Research Laboratory (NRL) Cyclotron was investigated. It is anticipated that the use of comparative genomics will provide information that will advance the understanding of mechanisms of pathogenesis and the importance of secondary metabolism in social microbiology. Variations in quality of care for AIDS patients were observed in a statewide managed care system. Employers are helping their employees overcome difficult times due to substance abuse.

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Gold-Catalyzed Cyclization of Furan-Ynes bearing a Propargyl Carbonate Group: Intramolecular Diels-Alder Reaction with In Situ Generated Allenes. Periprosthetic osteolysis is a major clinical problem that limits the long-term survival of total joint arthroplasties. This is a cyanide-assimilating strain which also grows in media containing cyanide-enriched effluent from the jewellery industry. The database and listing of 131 studies is available for use by suicide prevention researchers.

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These results support the hypothesis that different mutant proteins vary in their ability to disrupt nuclear organization and function. Light microscopy demonstrated an exuberant foreign body giant cell response surrounding and invading the substance of the graft, and also revealed evidence of graft degradation.

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This study compared epidemiology, risk factors, and short- and long-term outcomes for patients with community-acquired (CA) and hospital-acquired (HA) AKI. An approach is suggested which may help to differentiate feet genuinely at risk of ulceration from those merely unable to detect the 5.07 filament on account of thickened skin callus or advancing age. It was more frequent in white women, leu kodermics, without family history of glaucoma and with an age average of 59.6 years. The role of neuroimaging in this population includes early detection of direct HIV infection, opportunistic infections, neoplasia, or cerebrovascular diseases.

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We report a case of a 38-year-old man with a background of a neglected neurogenic bladder, who presented with a recent onset history of stress urinary incontinence. We noted the highest oviposition on the susceptible control genotype, CDC GO, and the lowest on one of the central Asian genotypes (NN-100) in both choice and no-choice tests. Clinical specialization expanded, leading in 1929 to the establishment of the Royal College of Physicians and Surgeons of Canada to accredit training and certify graduates. Both gp120 and Tat disrupt neuronal calcium homeostasis by perturbing calcium-regulating systems in the plasma membrane and endoplasmic reticulum.

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Histone acetylation and DNA methylation are major determinants of chromatin structure, and chromatin structure is a primary regulator of gene transcription. The oxidation of arsenite was rapid, but the adsorption of the generated arsenate was slow. Then the gene fragment was integrated into the multiple cloning site of pQE-30 and expressed in E coil. Space allowance and high fiber diet impact performance and behavior of group-kept gestating sows. Lys693 and Asp714 in the seventh and eighth transmembrane segments of ZntA contribute to the coupling of metal binding and ATPase activity.

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Nosocomial infection in pediatric surgical patients: a study of 608 infants and children. Hip fracture consumed one fourth of all somatic hospital bed-days for the oldest patients. We conducted a multicenter prospective descriptive study including patients with CA-GNB. Caff or Keto given individually reduced retinal neovascularization, but the two drugs given together prevented severe OIR. The resulting in vitro data were extrapolated to predict in vivo changes in DMXAA pharmacokinetics.

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As regards the timing and efficiency of chemical reactions in small systems, our simulations show that placing the reactive site at a central location may be favored at an early stage of growth but, as the system evolves in size, a location on the boundary becomes favored. Accurate, sensitive and reliable quantitative diagnostic tools can reduce the number of unnecessary biopsies, the associated morbidity as well as the costs of care in addition to improving survival rates. Visual guidance of landing behaviour when stepping down to a new level.

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Genetic risk factors should be more fully investigated in never smokers. Decomposition in soil microcosms of leaves of the metallophyte Arabidopsis halleri: effect of leaf-associated heavy metals on biodegradation. Equal nonbreeding period survival in adults and juveniles of a long-distant migrant bird. Radiographic predictability of hiatal hernia prior to gastric band surgery.

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This phase of the project confirmed that, in New South Wales, the most predictive variables were case type, functional status measures, impairment type for rehabilitation, phase for palliative care and severity of symptoms for palliative care. TGF-beta1 dose-dependently inhibited TNFalpha-induced production of RANTES protein and mRNA from RA FLS.

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These electrodes were introduced into the muscles through a rigid esophagoscope. The isolation and preparation ten years ago of the fullerenes in bulk quantities, sparked off a truly remarkable interdisciplinary research activity, encompassing diverse fields of chemistry, physics, materials science and medicinal chemistry.

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It is hoped the solutions presented here can help mitigate these difficulties. The information on environmental distribution offers clues for attempts to culture landmark representatives of these novel bacterial divisions, and the sequences are specific molecular signatures that provide for their identification in other contexts. Accurate, timely completion of the MDS is critical to success under PPS. The effect of JB (5, 10 or 50 mg/kg, p.o.) on defensive behaviors was also evaluated.

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Measurements of DNA ploidy, proliferation index and nuclear area were performed on 210 samples taken from 15 human colorectal tissues. To assess the extent that the genetic and environmental factors contribute to the phenotypic correlations between obesity traits and age at menarche (AAM), and also to examine the influence of AAM on obesity in both pre- and postmenopausal women. Consequently, for any developments of curcumin in the future, analogues of curcumin that have better bioavailability or substitute formulations are needed crucially. This admission presented organizational and administrative challenges.

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We propose a fast and powerful analysis algorithm, titled Model-based Analysis of Tiling-arrays (MAT), to reliably detect regions enriched by transcription factor chromatin immunoprecipitation (ChIP) on Affymetrix tiling arrays (ChIP-chip). Learning and memory are two of the most magical capabilities of our mind. Odds ratios (OR) were adjusted for age, energy intake and dietary fiber.

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We conclude that testosterone plays an important role in modulating the physiology of the vagina and contributes to improvement of genital sexual arousal responses. Impact of Enterococcus faecalis on the bactericidal activities of arbekacin, daptomycin, linezolid, and tigecycline against methicillin-resistant Staphylococcus aureus in a mixed-pathogen pharmacodynamic model.

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In contrast, both phentolamine- and nicardipine-treated ischemic rats showed no changes in either index compared with sham-operated controls. Furthermore, PGE2 promotes tumor growth in vivo by induction of CXCL1 expression, which results in increased tumor microvessel formation.

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The location of the mass and its CT characteristics aid in the formulation of a diagnosis. Outcomes were self-reported 7-day point prevalence abstinence rates at 1- and 6-month follow-up and continuous abstinence rates at 6-month follow-up. Non-diabetic twins underwent a hyperglycaemic clamp at 10 mmol/l. Mesoporous SnO2 with a high surface area of 292.7 m(2) g(-1) has been successfully synthesized via a low-cost NH4Cl-based ionothermal route. Oral administration of a novel chymase inhibitor, NK3201, prevents peritoneal adhesion formation in hamsters.

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The metabolites were accumulated on potato-glucose agar (PGA) while bacterium was cultivated on kapron membranes placed on surface of the medium. By the gradual multifactorial solution of these individual problems, the prolongation of the survival period of experimental animals was achieved.

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During the layover in the Far East, the sleep deficit diminished partly because of additional naps. Umbilical cord blood was collected following delivery of the infants and serum S100B levels were analyzed at the end of the study period. With the patient supine, a median sternotomy was performed without difficulty, and the ventricular septal defect was closed under cardiopulmonary bypass.

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Nursing emancipation is alive and well and living in Newcastle, according to a letter in a recent Lancet. Both circulating and mucosal antibodies are considered important for protection against infection by influenza virus in humans and animals. Toxic methemoglobinemia following the postoperative ingestion of 4,4-diaminodiphenylsulfone (DADPS)--on the differential diagnosis of cyanosis

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This effect was obtained by aiming 0.5-1.0 mm behind the limbus at a 1-mm defocus using 4 J of energy for the Nd:YAG and 1.2 J for the diode laser. The findings highlight the importance of mental health for intentions to retire early. Spleen cells from treated mice failed to mount an antibody response upon transfer to syngeneic gamma-irradiated recipients, suggesting that potential antibody-producing cells were impaired by the treatment. Marked sclerosis and osteophytes restricted to lumbo-dorsal spine, absence of ligamentous calcification and lack of long standing spinal symptoms in spite of the florid radiologic changes should raise the suspicion of neurogenic spinal arthropathy. Preference tests suggest that this simple and versatile odor receptor can serve as a model for investigation of molecular interactions between receptors and odorant molecules.

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Salmonella infections of food animals are of concern to both the food industry and to the public health authorities. Collagen nanofibers facilitated presynaptic maturation in differentiated neurons from spinal-cord-derived neural stem cells through MAPK/ERK1/2-Synapsin I signaling pathway.

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A survey of the technical aspects of endoscopic ethmoid surgery and an introduction of the extended range of indications are presented together with the results of each procedure. We review the clinical applications of electrochemical biosensors based on a few selected examples, including enzyme-based biosensors, immunological biosensors and DNA biosensors. A better knowledge of the biological and clinical behaviour of BRCA related cancers is of strategical importance in the management of patients with strong familiar neoplastic history or with genetic test positivity. The authors suggest that these types of acting out in general are a depressive equivalent, and a larger sample could duplicate the findings and collect more precise data about the nature of the relationship in the family of origin to help these women feel better in their social role. However, a brief treatment-test interval (30 min) resulted in a liquore con erba cedrina medicine greater suppression of intake and food-deprived rats were more resistant to the suppressant effects of fluoxetine than were sated rats.

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