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Orifungal (Ketoconazole)
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Ketoconazole

Orifungal is active against Candida spp., and Cryptococcus neoformans. However, its activity is limited compared to that of fluconazole and itraconazole. Furthermore, due to its limited penetration to cerebrospinal fluid, it is clinically ineffective in meningeal cryptococcosis. Its activity against the dimorphic moulds, Histoplasma capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Sporothrix schenckii, Paracoccidioides brasiliensis, and Penicillium marneffei is favorable. However, fluconazole and itraconazole are at least as effective as Orifungal against these fungi and are safer. Thus, Orifungal remains as an alternative second-line drug for treatment of infections due to dimorphic fungi. Orifungal is not recommended for treatment of meningeal infections due to Histoplasma capsulatum, Blastomyces dermatitidis, and Coccidioides immitis due to its limited penetration to cerebrospinal fluid. Orifungal is also active against Pseudallescheria boydii and is a good alternative for treatment of pseudallescheriasis. It is also effective in pityriasis versicolor. Orifungal has practically no activity against Aspergillus spp., Fusarium spp., and zygomycetes order of fungi.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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Flucomed, Domer, Cluvax, Oxybutynine, Meprim, Flagystatin, Fexofast, Spirolang, Omepral, Lansoprazole, Lanfast, Taromentin, Novamin, Clora, Cyclovir, Vitaros, Lupimox, Paroxetina, Ciloxan, Topra, Gabapin, Doneurin, Topilex, Omnexel, Quetin, Venla, Tambac, Viepax, Glevo,

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To determine the relationship between the parotid volume, parotid-planning target volume (PTV) overlap, and dosimetric sparing of the parotid with intensity-modulated radiation therapy (IMRT). Dynamic interconversion of amorphous microparticles and crystalline rods in salen-based homochiral infinite coordination polymers. To describe an outbreak of meningococcal meningitis and the impact of rifampicin chemoprophylaxis on secondary attack rates among Aboriginal people in central Australia. Hyperammonemia occurred in plasma after 8 hr and continued through 24 hr and was accompanied by an increase in serum urea nitrogen.(ABSTRACT TRUNCATED AT 250 WORDS)

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Human herpesvirus 8 glycoprotein K8.1: expression, post-translational modification and localization analyzed by monoclonal antibody. A typology describing the varied ways AA adolescents manage their depressive symptoms through interactions with other people was constructed and labeled Being With Others.

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Potency, however, is a complex function of the physical and chemical properties of both the active ingredient and its vehicle. First, we used the presynaptic alpha-2 noradrenergic agonist clonidine, which acts to decrease noradrenergic transmission. Predicting pressure ulcers: cases missed using a new clinical prediction rule. Seminal volume, sperm concentration, percentage of pathologic sperms were measured in all men. Next, we found that FoxF function is required downstream and in parallel to the FGF/MAPK/Ets cascade for cell migration.

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This case report clearly indicates that the remaining risk of transfusion-related transmission of HIV could be severely reduced, not only by the use of NAT screening but even by HIV antigen screening or more sensitive HIV antibody assays. Later, in the recovery phase, MBP 63-88 induced lymphoid cells to TGF-beta production. Effects of pregnancy and female sex steroid hormones on calcitonin gene-related peptide content of mesenteric artery in rats. In this study, antisense oligonucleotides complementary to c-fos mRNA were employed to interfere with the expression of Fos protein. Zolpidem is a rapid-onset, short-duration imidazopyridine hypnotic drug and is specific agonist of the omega-1 (BZD1) receptors.

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This finding suggests the potential harmful influence of childhood emotional neglect on the development of spirituality in psychiatric patients. Simulated circulations converge to yield nearly the same zonal winds when initialized with both stronger or weaker rotation rates. The relationship between uncinate fasciculus white matter integrity and verbal memory proficiency in children. Chronic post-traumatic headache (CPTHA), the most frequent complaint after traumatic brain injury (TBI), dramatically affects quality of life and function.

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Fast-acting excitatory amino acids are involved in the enhancement of the aversiveness of the electrical stimulation of the inferior colliculus by systemic injections of muscimol. Blood conservation strategies have been found to reduce the volume withdrawn for laboratory tests, but some patient populations may remain at risk. Follow-up remains important to obtain as much up-to-date information as possible. In liquid cultures of peripheral blood cells, the number of small basophils initially present decreased and large basophilic cells appeared over a 2-week period. The purpose of this study to compare the outcomes of two different methods, spinal anesthesia and ilioinguinal-hypogastric nerve block (IHNB) with target concentrated infusion of remifentanil for inguinal herniorrhaphy.

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In vivo, tumor cells receive survival signals from the extracellular microenvironment. This reduction in luminal volume lasted for approximately 4 min. To determine the normal retinal nerve fiber layer (RNFL) thickness as measured by optical coherence tomography (OCT), and to evaluate the relationship between RNFL thickness in healthy Japanese and their age.

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Leukocyte counts and lymphocyte counts of 100 patients operated by thoracotomy have been determined preoperatively and on the postoperative 3rd hour, and 1st, 2nd, 3rd, 5th days. Determining how species adapt to environmental change is paramount. In this prospective, randomized, double-blind study, we evaluated whether a very low dose of spinal bupivacaine could be sufficient for safe performance of short perianal surgery. Anxiety disorders are among the most frequently encountered psychiatric disorders.

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Thus, MNs in the cervical spinal cord appear to use intracellular pathway(s) for early PCD that is responsive to Bcl-2. Human umbilical vein endothelial cells (HUVECs) treated with SalA were subjected to IS/RP stimulation. This induces the corresponding conformational changes in other proteins with identical or similar sequences. However, the emergence of imatinib resistance and the incomplete molecular response of a significant number of patients receiving this therapy have led to a search for combinations of drugs that will enhance the efficacy of imatinib. Roseomonas bacteremia in a recipient of an allogeneic hematopoietic stem cell transplantation.

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Both proteins undergo extensive physiologic regulation, principally through phosphorylation, as well as specific disease-induced pathologic modifications, including phosphorylation, oxidation, and proteolysis. The excised tumor was 11 x 9 x 5 cm in size and was diagnosed histologically as leiomyosarcoma of the esophagus without any nodular involvement. Effects of essential fatty acid deficiency and carbon tetrachloride-induced liver cirrhosis on lipid and fatty acid compositions of oral palatal epithelium in rats.

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Nineteen patients have required antihypertensive therapy, five have suffered ischaemic heart disease and two a cerebrovascular event. These changes in ventricular function may precede morphological derangements observed in later developmental stages. The flaps were harvested through limited skin incisions with the aid of lighted retractors. The results are difficult to explain by certain connectionist theories of discrimination learning, unless they are modified to take account of the way in which compound stimuli are structured.

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We report on two patients with large burn injuries who acquired vancomycin-resistant enterococcal septicaemia during their in-patient stay. The case report presented here is an example of prolonged QT interval syndrome in a patient with cocaine abuse and electrolyte disturbances. Developmental differences were observed in most but not all of the processing variables. To test this idea, we examined interactions between IC1, IC2 (another intermediate chain) and ODA-DC using recombinant proteins.

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This article describes the development of a proximal interphalangeal (PIP) joint prosthesis based on the principles of replicating anatomical surface components, the use of macrolocking intramedullary stem and the use of a cobalt-chrome alloy material. Film contrast, relative speed, and resolution of Fuji Super HR-G panoramic film were determined according to specifications of the American National Standards Institute and compared with those of Kodak T-mat G panoramic film. Prevention and therapy of squamous cell carcinoma of the rodent esophagus using freeze-dried black raspberries. This large single-center experience demonstrates that laparoscopic right donor nephrectomy performed without hand-assist devices is safe and yields kidneys with excellent function.

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The mechanism of proton transfer between adjacent sites on the molecular surface. A standard instrument for the assessment of the appropriateness of hospital care with known metric properties may be useful for quality management in hospitals and provide competitive advantages in a consolidating health care market. Effect of estrogen/progestin administration on the ovarian response to gonadotropins: a randomized, prospective study. Pediatric care, particularly that provided in pediatric intensive care units, is sufficiently different from adult care that specific metrics are required. Many of these treatments are merely palliative and do not eliminate the complex immune response initiating the symptoms, so there is a recurrence of disease as soon as the therapy is discontinued.

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We report here a new class of self-assembling peptide inspired by a 20 kDa barnacle cement protein. If so, the relative ease in producing oocytes in this way could facilitate the identification and characterization of the factors. A treatment strategy of first-line olanzapine was shown to be cost saving over a 1-year period, with additional clinical benefits in the form of avoided relapses. These findings suggest a novel mechanism for anti-atherogenic actions of HDL through its S1P component.

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Hence, r-hirudin is suitable for studying platelet functions at physiological calcium concentrations. Estimating the relative contributions of mutation and recombination to clonal diversification: a comparison between Neisseria meningitidis and Streptococcus pneumoniae. Calculations presented in this paper suggest that supernovae and gamma ray bursts are likely to produce sea-level radiation exposures of about I Gy with a mean interval of about five million years and sea-level radiation exposures of about 0.2 Gy every million years. The increase in CT was more pronounced in patients where fluids were warmed under the warming mattress (Group M) than in those with fluids warmed by a coil warming device (Group T).

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The results showed that embryo implantation was significantly inhibited in the mice injected with 3 microg E-cadherin antibody. Subclass determination showed that all three MAbs secreted IgG1 type of antibody. Safety and efficacy of Danqipiantan capsule for treatment of stroke: a systematic review.

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IFN-kappa was particularly effective in inhibiting inducible IL-12 release from monocytes. Normal human diploid cells have a limited life span and undergo replicative senescence after various limited population doublings. The Convention includes provisions on providing technical assistance and capacity building, particularly for developing countries and countries with economies in transition, to promote its effective implementation. Four groups of weanling rats were fed semisynthetic diets containing 15 percent by weight of dietary fats for 28 days.

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Three days after the last irradiation, samples of aqueous humor were aspirated, and the metabolic profiles analyzed with (1)H NMR spectroscopy. This article reviews the current understanding of alterations affecting oncogenes and tumor-suppressor genes associated with urothelial carcinoma, and their application in the context of morphology and classification schema. Water Concentration Analysis by Raman Spectroscopy to Determine the Location of the Tumor Border in Oral Cancer Surgery.

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Conventional assays of cell survival determine only the proportion of colony-forming cells, assuming that all such cells are equivalent. A local denervation of the paravertebral muscles was found in post-discotomy syndrome. Getting closer to the truth: overcoming research challenges when estimating the financial impact of worksite health promotion programs.

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In these cases the composition heterogeneity causes more enhanced viscoelastic heterogeneity and the macroscopic stress is decreased at fixed applied shear rate. Leukemoid Reaction (LR) is defined by reactive increase in leukocyte count of more than 50,000/cu mm with increase in mature leukocytes on peripheral blood. It is shown on multilamellar phospholipid systems that the deuterated segments can be used as structural probes. Many new stool tests intended to detect neoplastic cells or cell products are developed at present for colorectal cancer (CRC) screening.

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Starting by an historical brief review of the evolution of this discipline, the two main streams in which this field is nowadays divided are examined. Our in vivo optical imaging results using H22 tumor-bearing mice show clearly the selective accumulation of ATF-ZnPc in tumor region, thereby revealing the great potential of ATF-ZnPc for clinical applications such as cancer detection and guidance of tumor resection in addition to photodynamic treatment.

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In this paper a novel statistical method for curve fitting is described and applied to growth data for illustration. Autocrine and/or paracrine mechanism operate during the growth of human bone marrow fibroblasts. Yet quality assessment is a complex task that involves precise determination and specification of useful measures. This was a prospective, multi-center, single-arm, open-label study conducted in Chinese dyslipidemia patients with high CV risk. Stimulation by EGF resulted in the recruitment of Grb2-YFP and YFP-Shc to cellular compartments that contained EGFR-CFP, and a large increase in the FRET signal.

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In this study, we show that human cord blood-derived mast cells (CBMC) can be infected by pathogenic S. Simple interventions delivered during pregnancy have considerable potential impact on important mortality outcomes. At first sight, there would seem to be no reason for signaling pathways of this type to require oscillations.

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Equol producers seem to present a more positive response to isoflavone intervention. A study on reconstruction of ossicular chain by an in situ bone tissue engineering technique. Possible predictors of treatment outcome in cognitive therapy (CT) and exposure therapy (ET) for hypochondriasis were investigated. Furthermore these results contribute directly to current experimental projects on the use of material for documentation.

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Commissurally projecting entorhinal neurons were found in layer II, confirming previous anatomical studies. Seven commercially available ionic liquid columns were tested using a test mixture containing 37 fatty acid methyl esters. Life history analysis comprised survival, individual growth, reproductive traits and life table parameters.

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These include peptide-based vaccines, engineered hypoallergens with reduced reactivity for IgE antibodies, nucleotide-conjugated vaccines that promote Th1 responses, and the possibility of developing prophylactic allergen vaccines. Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists. Transport medium consisted of 1 mL of sterile saline or thioglycolate.

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Suppression of beta rhythms was also stronger during synchronization preceded by syncopation, e.g., after subjects had switched, when compared with a control condition in which subjects synchronized throughout the entire range of rates. A main shortcoming of prior studies was the focus on a mixture of waste with different characteristics. Leucocytozoon smithi: incidence of transmission by black flies in South Carolina (Diptera: Simuliidae).

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Overexpression of a constitutively active PKB led to induction of PAI-1 mRNA expression and of luciferase (Luc) activity from a gene construct containing 766 bp of the rat PAI-1 promoter. This fluorescence in situ hybridization protocol for repetitive DNA probes results in yellow-green fluorescent signals on orange-red stained chromosomes. Immunosuppressive regimens administered to recipients after organ transplantation might be used as a therapy of autoimmune hepatitis in multicenter clinical trials. To evaluate for cohort effects, United States Medical Licensing Examination (USMLE) Step I scores for these 2 groups were also compared. In this study, we demonstrate that prospectively isolated CD271pos/CD140alow/neg BMSCs expressed high levels of hematopoiesis supporting genes and signature mesenchymal and multipotency genes on a single cell basis.

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MicroRNAs (miRNAs) are 21 to approximately 25-nucleotides (nt) long and interact with mRNAs to trigger either translational repression or RNA cleavage through RNA interference (RNAi), depending on the degree of complementarity with the target mRNAs. We demonstrate experimentally and computationally that the features of the buckling pattern depend on the magnitude of stretching, and this observation offers a new way for controlling the shape of a swollen homogeneous thin sheet.

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A pedal path realized by a three-bar linkage that was optimized according to preliminary simulations further increases leg cycling efficiency. Report of group A of the American Cancer Society Research Workshop on Cancer and Nutrition: panel on human studies. Calcium-related changes of enzyme activities in energy metabolism of cultured embryonic chick myoblasts and myotubes. A Case of Rectal Neuroendocrine Carcinoma with Metachronous Liver Metastasis Treated with Multimodality Therapy We report a typical case of a 21-year-old male with recent onset of smoking, who presented with acute febrile hypoxemic respiratory failure.

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How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis. She had been admitted to the hospital following secondary generalized seizures of 35 min duration. As more anti-angiogenic agents proceed through clinical development, it is important to consider what we now know about the effects these agents have on the tumour vasculature and what aspects of tumour angiogenesis remain to be elucidated. There exists HIV-1 subtype E infection in population of non-remunerated blood donors in Shenzhen.

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In this study, the authors investigated the value of SPECT abnormalities to guide psychosurgery and correlated the surgical results with the postoperative SPECT. siliqua and a prevalence of hexa- hepta and octa-chlorinated biphenyls in M. Behavioral variation among colonies has consequences for survival and reproductive success that are the basis for evolutionary change. One is based on the Euclidean match factor, and the other is based on the identification of specific peptide peaks occurring exclusively within one group of persons.

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Prospective, randomized, double-blind, placebo-controlled, crossover study. E1j, a quantitative variant at cholinesterase locus 1: immunological evidence. Semiquantitative assessment of tibial artery calcification by computed tomography angiography and its ability to predict infrapopliteal angioplasty outcomes. The exact solutions for the isotopic compositions and the concentrations of the two-reservoir model for mantle-crust evolution are given for arbitrary rates of crustal growth and of back flow to the mantle. It is the intent of this review to provide a working model of this defense system as it operates under both open and closed eye conditions, to provide evidence in support of this model as well as highlight some of the many areas of uncertainty.

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Tests have been evaluated in terms of their potential to provide information on feasibility, degradation rates and residual concentration of bioremediation in the vadose zone. Increased mean platelet volume in patients with infective endocarditis and embolic events. An original aspect of the rod visual cell in the carp (Cyprinus carpio)

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Ruthenium-catalyzed oxidative cyanation of tertiary amines with molecular oxygen or hydrogen peroxide and sodium cyanide: sp3 C-H bond activation and carbon-carbon bond formation. High-performance liquid chromatographic determination of 1,2,3,4-tetrahydroisoquinoline in rat brain with fluorescence detection.

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The clones containing recombinant ciproxin 500 tablet plasmids were screened for the CAMP reaction with Staphylococcus aureus. Tract-tracing experiments combining the anterograde method with the retrograde one indicated that the interposed and lateral cerebellar nuclei projected to the posterior parietal cortex mainly through the nucleus ventral lateralis caudalis of the thalamus. Patients with a higher symptom burden warrant more detailed assessments and may have therapeutic needs that would not be identified using current classifications based only on respiratory function.

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Pressure-flow relationships for packed beds of compressible chromatography media at laboratory and production scale. The wire from this spring bifurcates near the proximal end of the catheter. The integration of this knowledge is crucial to the identification of the regions responsible for the amyloidogenic and aggregating behavior of a given protein. A wide range of victrelis price uk algorithms are available for promoter prediction. These results suggest that the verbal factor has a different effect on the neural networks for facial emotion, processing.

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Postoperative hypothermia initiates an increased oxygen demand in the postoperative period and may endanger patients with restricted cardiopulmonary reserves. The severe intrauterine exposure cases are well known, although the possible impact of low-to-moderate methylmercury exposure side effects augmentin 875 mg in utero are rarely investigated. Patients who were found to have no coronary artery disease on CT-CAG were recruited in this study.

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We conclude that thrombin-released bFGF binds to syndecan-4 and FGFR-1, which is required for thrombin-induced mitogenesis and migration. On the basis of these data, the concept of a dynamic nature of the dopamine effects in a circadian spirolang 50 acne products context is presented.

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EGF treatment induced the change of EMT markers and increased cell migration. Using multivariate models, kumon mandal vikas nigam ltd vs girija shankar pantoprazole the authors found that use of antipsychotic medications, age, and disability were strong predictors of developing self-reported Parkinson disease (PD) in the subsequent year among 1992 to 2000 Medicare Current Beneficiary Survey participants.

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Both SMI1 and SMI2 have similar amino acid composition, suggesting that they may be structurally related. We show highly repeatable and specific formation of biofilms that resemble clinical biofilms equate omeprazole magnesium by a commonly studied laboratory strain and ten cystic fibrosis isolates of this key opportunistic pathogen. Assessment of water systems for contaminants from domestic and industrial sewages. Accordingly, normal rat brain and intestine were immersed in formalin after postmortem intervals (PMI) from 0 to 72 hours (h) or were fixed by perfusion with ethanol or paraformaldehyde-glutaraldehyde (PF-G). If the particle is a light scalar, this induced coupling leads to spin-independent non-Newtonian forces.