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WilcoxCV: an R package for fast variable selection in cross-validation. Expression and clinicopathological significance of Mel-18 mRNA in colorectal cancer. Creutzfeldt-Jakob disease: a new view on an old problem (clinics, diagnosis, prognosis, treatment)

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Associations between the outcome and planned mode of delivery were controlled for confounding by multivariate analysis. After the behavioral testing, PV-immunoreactive neurons in the brain were immunohistochemically analyzed. Our data indicate that the mammalian SD is composed of NEPHRIN and NEPH1 molecules, while NEPH2 and NEPH3 do not participate in podocyte intercellular junction formation.

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Bronchial reactions to carbachol inhalation in patients with a suspected diagnosis of cough due to asthma Extracted information included study design, sample size, description of the intervention and control condition, pressure ulcer outcome measures, and corresponding results. Gastrointestinal symptoms in children should be thoroughly evaluated and standard screening for colonic polyposis should be performed in all individuals with a positive family history and/or known mutations in cancer-associated genes, particularly in children who are under 10 years of age. Uncorrected (UDVA) and corrected (CDVA) distance visual acuity, Visual Function Index-14 (VF-14) scores, and spectacle dependence were assessed prior to surgery and 6 months postoperatively. A review of natural products as leads to potential therapeutic agents.

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Except three who were entrained to 24 h by an externally controlled light-dark cycle (LD), subjects had no time cues and developed free-running circadian rhythms either in self-selected LD-cycles or in constant illumination. Enzymatic, functional and morphological test are used for the diagnosis of pancreatic diseases. The results are helpful not only for understanding the living behavior of some aquatic creatures but also for the design of biomimetic soft microrobotics. A male, juvenile rat was exposed twice to an adult male rat at intervals of 60 or 90 min, and release of ACh and glutamate was determined in the NAc of the conscious adult rat. The structures of erythrolides K and P were confirmed and their relative stereochemistry determined by X-ray crystallographic analysis.

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Rebleeding in patients with primary intracerebral hemorrhage is considered uncommon, but there are no precise data to support this opinion. Chronic lymphocytic leukemia-associated paraneoplastic pemphigus (bullous pemphigoid-like). However, Gulf War veterans reported these same clusters with greater frequencies than did nondeployed veterans. Induction of the 72-kilodalton heat shock protein and protection from ultraviolet B-induced cell death in human keratinocytes by repetitive exposure to heat shock or 15-deoxy-delta(12,14)-prostaglandin J2. This study retrospectively analyses the initial experience of liver transplantation (LT) in the Indian Armed Forces.

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A very fast fungicidal activity was shown by 0.2, 50, and 30 mg/mL of benzydamine, lidocaine, and bupivacaine, respectively. c-Myc-induced, long, noncoding H19 affects cell proliferation and predicts a poor prognosis in patients with gastric cancer. We suggest a stimulatory effect of TSH able to produce considerable changes of the immune response and immune tolerance in patients with AT causing target organs damage. The On VIM and On VOA/VOP conditions did not differ significantly from each other in terms of contralateral upper extremity symptoms or total clinical score.

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Thus, increased production and action of ANG II specifically in the subfornical organ are sufficient on their own to mediate an increase in drinking through PKC. Expression of functional lung resistance--related protein predicts poor outcome in adult T-cell leukemia. To further understand the role for NK cells in inflammation, we investigated the phenotype and function of synovial fluid (SF) NK cells from patients with chronic joint inflammation, as well as from patients with transient inflammation of the knee following trauma. Two Brantigan cages were adequately placed via a single portal, and reliable bilateral anterior-column support was achieved.

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The proposed unit-cell-based micromechanical model represents a statistically average realization of the actual network and gives the average mechanical properties, such as the shear modulus. The conceptual framework consists of 5 components that can be considered in relationship to each other: macro context, mission, structural capacity, processes, and outcomes. We discuss potential mechanisms of action for Bcl-3 and Bcl-6 in this highly complex, but important process of B-cell affinity maturation.

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Transport in asymmetrically coupled donor-based silicon triple quantum dots. LDS patients often harbor additional aneurysms and dissections throughout their vasculature. Taken together, these results suggest that IkappaB ubiquitination inhibitor may have therapeutic potential against asthma. Usefulness of low-dose dobutamine echocardiography in idiopathic dilated cardiomyopathy.

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Cytokine-mediated induction of the human elafin gene in pulmonary epithelial cells is regulated by nuclear factor-kappaB. Short communication: Genomic selection in a crossbred cattle population using data from the Dairy Genetics East Africa Project. However, the breadth of the genetic heterogeneity of HCV is great, and this may have important implications in diagnosis, pathogenesis, treatment, and vaccine development. To improve their functionality as a nanomedicine for diagnosis and therapy, the vesicle fusion and layer by layer approach were employed. Probable sources of syphilis introduction into and transmission within prisons included mixing of prisoners with unscreened jail populations, transfer of infected inmates between prisons, and multiple concurrent sexual partnerships.

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The measured PITS was compared with the pivot-shift grade with patients under anesthesia in a subgroup of 87 isolated ACL-insufficient patients with no other knee injury. Synthesis of Quinolines via a Metal-Catalyzed Dehydrogenative N-Heterocyclization. From this new term, we propose two different estimation strategies, depending on whether we explicitly know the type of relations between the different scales (as for physical processes) or not. Isoproterenol increases Cl diffusion potential difference of rabbit trachea through nitric oxide generation. Neutralizing antibodies to VEGF significantly inhibited the decrease in BAEC electrical resistance caused by CrAg.

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Infection of a canine macrophage cell line with leishmania infantum: determination of nitric oxide production and anti-leishmanial activity. Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors. Projects have to be actively managed, users have to be willing participants and data has to be analysed. Over the past years the number of medical registries has increased sharply.

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Within the teleosts, several subsequent independent duplication events occurred that led to several GHR subtypes. In conclusion, the deregulation of IGF signalling pathways, which often occurs during liver tumorigenesis, does not necessarily require IGF-IRs, and hepatic IGF-IR alone may not play a determinant role in c-myc-induced hepatocarcinogenesis. Wikipedias: collaborative web-based encyclopedias as complex networks.

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The acute central haemodynamic and neuroendocrine effects of intravenous flosequinan were studied in a group of 10 patients with severe heart failure. Acute exudative inflammation and nasally exhaled nitric oxide are two independent phenomena. We attempted to estimate the excess annual costs that a US private employer may attribute to employing an individual who smokes tobacco as compared to a non-smoking employee. The emergence of nanotechnology has already had a groundbreaking impact in biomedical research.

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pylori to laminin is mediated by the sialic acid-binding adhesin, SabA. In 127 pregnancies an amniotic fluid specimen was obtained within 72 hours of delivery.

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CD33 is expressed on the malignant blast cells in most cases of acute myeloid leukemia (AML) but not on normal hematopoietic pluripotent stem cells. medicae is maintained even though these bacteria can cooccur in sympatry on the same individual host plants. Evaluation of Bupleuri Radix resources in Qingchuan based on DTOPSIS and grey related degree The increase in amino acid uptake not only may support de novo protein synthesis but, in the case of glutamine, also may be required for energy production and nucleotide biosynthesis. Early postoperative endoscopy for targeted management of patients at risks of anastomotic complications after esophagectomy.

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Alterations of voltage-activated sodium current by a novel conotoxin from the venom of Conus gloriamaris. Important aspects of the obesity epidemic such as the role of the food industry, fast food chains, advertising, and a lifestyle that limits children to sedentary activities and overeating cannot be explored by a traditional clinical trial design. We successively review, from some important examples, the classical methodological approach for discussing causality in epidemiology. As in the Shinnar-Le Roux (SLR) approach, we use a hard pulse approximation to actually design the pulse.

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Initially we used a posterior approach with total facetectomies. This hemoglobin variability may cause left ventricle hypertrophy and may increase mortality as well. Serine and cysteine protease-like genes in the genome of a gall midge and their interactions with host plant genotypes. Both NI (II) and Hg (II) decreased the phenolic contents, while Cu (II) increased it to some extent. The effect of electroconvulsive shock seizures on behaviour induced by dopaminergic agonists and on immobility in the Porsolt test.

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Se-methylselenocysteine induces apoptosis mediated by reactive oxygen species in HL-60 cells. Quantum-chemical calculations confirmed and explained the preference for the gauche conformations of adsorbed trioctyl-TATA.

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The Eastern woodchuck, Marmota monax, has been a useful model system for the study of the natural history of hepadnavirus infection and for the development and preclinical testing of antiviral therapies. The present study was conducted to identify significant demographic, illness-related, and physiological factors associated with recovery at 1 month after brain injury, and to develop and evaluate a Decision Tree Analysis-based prediction model. A device to facilitate kinetic receptor filtration assays is described.

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The angle of cell division is critical in at least two contexts. We analyzed genetic variation on the Y chromosome, X chromosome, and mtDNA of the greater white-toothed shrew, a species with low variance in male reproductive success and limited sex-biased dispersal, which enables us to control to some extent for life-history effects. Effects of disorder on synchronization of discrete phase-coupled oscillators.

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Determination of serum levels of sCD25, sCD30 and IL-13 is not useful in everyday practice. In all patients and in all 5 of the controls, the dorsal root ganglion of every root was enhanced clearly. Lung transplantation provides a therapeutic option for patients with scleroderma with end-stage lung disease. Since AIDA-I harbors an N-terminal extension in its signal sequence, we wondered whether glycosylation requires this unusual sequence. Starting from loading spatial and spin patterns of atoms in optical superlattices as pure quantum states from a Fermi gas, we adiabatically transform this state to an RVB state by a change of the lattice parameters.

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The statins strongly inhibited the growth of all species, except Candida krusei. The first group - Control, the second with topical use, and a third group with injected mitomycin C reinforcement, monthly for 2 months. The purpose of this study was therefore to investigate the ability of an IVRT to select the topical semisolid formulations with the most rapid release rate of the model drug ketoprofen from two closely related hydrogels in a simulated product development process. This paper presents a critically reflective account of our experience of the actual value of undertaking qualitative research alongside a pilot cluster randomised controlled trial of a guided e-learning intervention for managers in an NHS Mental Health Trust to improve employee wellbeing and reduce sickness absence.

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However, distinguished from the transmembrane-like domain, these mutants preserved pro-apoptotic activity of IEX-1 fully. Experimentally determined tissue air ratios and scatter air ratios for collimated beams of 14 mev neutrons. Data collection included coexisting morbidity, rheology data (immunoglobulin level, hematocrit, and blood viscosity), clinical examination results, and OCT findings. Chemoradiotherapy seems to affect expression of COX-2 and Ki67 which indicates that these proteins might be of importance in predicting long-term outcome. Implications for Rehabilitation Depression is a common condition in adults with low back pain (LBP), and is associated with poorer patient outcomes.

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Late effects of post-high-dose-rate brachytherapy for oropharyngeal carcinoma: are they severer than post-low-dose-rate? Analysis of Flavonoid in Medicinal Plant Extract Using Infrared Spectroscopy and Chemometrics. This study compares, by use of a common protocol, the corneal physiological response to variations in fit of a new styrene-type gas-permeable hard (GPH) lens to those of other contact lens materials previously studied.

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A thermocouple was placed in the center of the cement mass, and the temperature-versus-time measurements were recorded. However, using high cell density cultivation, most DsrS was found cell-associated indicating current limitations of the production process. Cardioversion with flecainide in patients with atrial fibrillation of recent onset. To comprehensively elucidate the controversial hybridization mechanism of glucans with synthetic polymers, the hybridization behaviors of triple-stranded curdlan (Cur) and schizophyllan (SPG) with cationic polythiophene (PyPT) were investigated in aqueous DMSO solutions by using UV-vis, circular dichroism (CD), fluorescence, fluorescence excitation, and NMR spectroscopy methods, as well as theoretical calculations, dynamic light scattering, and zeta potential measurements. After common fusion and screening, the subtypes, titer and affinity of mAbs were detected respectively.

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PARTICIPANTS: Sixteen interviews were conducted, 13 with athletic training students and 3 with individuals identified as mentors. The smallest of the microsystem screws are 0.8 mm diameter and all are available in 2, 3, 4, 5, 6, 8 mm lengths.

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Microphotographic black-and-white pictures from the histologic adrenal cortex specimens were taken with a magnification of 800. Determination of virulence and multidrug resistance genes with polymerase chain reaction method in vancomycin-sensitive and -resistant enterococci isolated from clinical samples.

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Chasing dideoxy-mediated sequencing reactions with terminal deoxynucleotidyl transferase may result in nucleotide inversions in sequencing gels. Genome-wide QTL and bulked transcriptomic analysis reveals new candidate genes for the control of tuber carotenoid content in potato (Solanum tuberosum L.). Multifaceted approach to medication use policy development: the restriction of meperidine. This paper presents a result on information preserving compression of NMR images for the archiving purpose. Furthermore, when detected, there seems to be little survival advantage associated with prenatal diagnosis.

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Motilin in the amygdaloid nucleus has effects on the duodenal MMC cycle duration, the amplitude of phase III and the frequency of phase III, all of which may rely on either the effects of noncholinergic and nonadrenergic neurons on duodenal smooth muscle, or the increase of local motilin via nucleus amygdalae-hypothalamus-brain stem-vagus pathway. Short-course isoniazid and rifampin compared with isoniazid for latent tuberculosis infection: a randomized clinical trial We aimed to investigate incidence rates of urinary tract infections in Dutch general practice and their association with gender, season and urbanisation level, and to analyse prescription and referral in case of urinary tract infections. We present a case report of an incidentally found signet ring cell adenocarcinoma of a female urethral diverticulum. Promotion of next generation primary care physicians: initiatives in the university training of medical students

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These changes were visible more than a year after instillation of quartz and at least 3 months after instillation of anthracite dust. The polymorphisms of 32 microsatellites in 13 families of Wuzhishan pig in Hainan were Analysed. An equally important area of expertise--political skills--has been virtually ignored.

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2H NMR spectra were obtained for dimyristoylphosphatidylcholine multilamellar dispersions, perdeuterated in the fatty acid chains, in the presence and absence of two steroid analogs. PDT probably causes NPC cell apoptosis through an upregulation of the pro-apoptotic protein Bak expression. Federal tax developments affecting health care organizations--Part 1: New legislation.

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Gap junctional proteins of animals: the innexin/pannexin superfamily. Proteus mirabilis is a gram-negative bacillus that generates hydrogen sulfide. Epigenetic influences on the lifespan of the Drosophila: existence of an optimal growth temperature for adult longevity. Resource utilization included physician office visits, diagnostic imaging, emergency room use, inpatient hospitalization, opioid prescriptions, migraine prophylaxis prescriptions, and acetaminophen or nonsteroidal anti-inflammatory prescriptions. In order to assess the role of synapse formation in the regulation of motoneuron number, synaptogenesis was quantitatively examined after chronic neuromuscular blockade, which prevents motoneuron cell death.(ABSTRACT TRUNCATED AT 400 WORDS)

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Partial hydrolysis of the amino acid-amino acid bond between residues A1 and A2 occurs in two cases: i) when residue A1 is loosely bound to subsite S1 and/or, ii) when residue A2 is firmly bound to subsite S1. This study presents the design of a virtual lung temperature sensor to control core temperature. However, detection of SF monosodium urate and calcium pyrophosphate dihydrate crystals, even from un-inflamed joints during intercritical periods, allows a precise diagnosis of gout and calcium pyrophosphate crystal-related arthritis. The results were geographically presented in maps by using ArcView mapping software. Ureteropelvic junction obstruction: long-term followup of adults with and without surgical treatment.

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Patients infected with HCV mount a humoral immune response to epitopes of HVR1. Pupillary diameter was significantly reduced when 10(-9) M or 10(-7) M ET-1 solution was injected. The thiazolidinediones have been shown to reduce insulin resistance, improve the ability of beta-cells to produce insulin, and decrease cardiac risk factors.

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This part of the operation stabilizes and decreases the blood supply to the ovary. An immunofiltration technique for the semiquantitative assay of human chorionic gonadotropin (hCG) was applied in two versions, using different antibodies. Evaluation of predictability for vancomycin dosage regimens by the Bayesian method with Japanese population pharmacokinetic parameters. The relationship between the social network and physical health has been studied extensively and it has consistently been shown that individuals live longer, have fewer physical symptoms of illness, and have lower blood pressure when they are a member of a social network than when they are isolated.

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Activation and inactivation of nuclear factor of kappa light chain gene enhancer in B cells (NFKB) is tightly regulated to ensure effective onset and cessation of defensive inflammatory signaling. Percutaneous transvenous embolization for portosystemic shunts associated with encephalopathy: Long-term outcomes in 14 patients.